Educational Dialog, very interesting! You may have heard the term “zombie cells.” In scientific language, these are called senescent cells. As skin ages or experiences environmental stress, some cells stop functioning optimally. They remain present in the skin but no longer contribute to firmness and vitality the way healthy cells do. Alpine Rose Active has been studied for its ability to support the skin’s natural processes involved in managing these fatigued cells. Rather than forcing aggressive turnover, this ingredient supports the skin’s own renewal pathways, helping maintain a more vital and resilient appearance over time.
Experience the future of rejuvenated skin with Garden of Wisdom’s Rose Stem Cell and Peptide Serum, a luxurious, concentrated treatment enriched with protective PhytoCellTec™ Alpine Rose Stem Cells, Alpine Rose Active, and advanced anti-aging peptides, including Argireline® and Syn®-Coll. These potent actives work synergistically to target fine lines, wrinkles, and loss of firmness, promoting visibly smoother and more youthful-looking skin. Read More Here on Our Blog
To further elevate its effectiveness, we’ve infused this serum with three of the most potent antioxidants known to skincare science: Resveratrol, known for its telomere-protective and skin-revitalizing properties, and Superoxide Dismutase is a powerhouse enzyme that neutralizes damaging free radicals at the cellular level.
This highly concentrated, water-free formula is designed to protect, rejuvenate, and restore, helping your skin maintain a luminous, youthful glow.
When we created this formula, our own skin care consultant, Jen, personally tested it to ensure its excellence. Her experience says it best:
"This serum is smooth and really lovely to put on! It’s fantastic for smoothing lines and wrinkles, reducing puffiness under the eyes, hydrating deeply, and leaves the skin feeling plump and refreshed. Plus, it has a sensual, soft scent that makes the experience even more luxurious. Just remember - it’s very concentrated, so a little goes a long way!"
Indulge your skin with the transformative power of our Rose Stem Cell & Peptide Serum - Floral Peptide Infusion for Renewed Skin Vitality, is a sophisticated blend of science, nature, and timeless beauty.
Shelf Life and Storage Information for Our Products and Ingredients
Finished Products - generally don't need to be refrigerated as they are preserved, but you can refrigerate them to extend their shelf life. The shelf life for most products is 9-12 months. Vitamin C Serum(s) and VitaResurface products should continually be refrigerated to extend their shelf life. Sample Sizes - do have a shorter shelf life (generally 3-6 months), and items in jars can dry up quicker than this if the lid is not tightened well enough (Vitamin C Serums - use within 90 days).
Please Keep Your Products Out of Humidity, Heat, Direct Light and in a Dark Cabinet When Possible
Exfoliating Acid - products have a shelf life of 9-12 months. The only things we don't suggest refrigerating are the Mandelic Acid Serums or Salicylic Acid Serums, as they can crystallize in the refrigerator. If this happens, you can set the product into a hot water bath to see if the crystals will dissolve.
Additional Items That Require Refrigeration and/or Kept in the Dark
Hydrosols and Distillates - remove 1 ounce of hydrosol and add it to a separate, sterilized spray bottle and spritzer. Keep the larger bottle in the refrigerator. Carrier and Exotic Oils - generally refrigerate all carrier oils, although some very rich oils will solidify. This is fine. All you have to do is take the oil out, warm it up at room temperature, and it should liquefy. If not, set the bottle in a hot water bath and occasionally shake the bottle, which will hopefully turn into a liquid. Some oils, like coconut cream and jojoba oil, have a super long shelf life.
Refrigeration of The Following Ingredients is Not Necessary, But it Won't hurt
Essential Oils - essential oils are best stored in a cool, dark place. Co2 Extracts - these should continually be refrigerated. Butters - we suggest refrigerating our "skincare" butters. You can remove what you need and keep the rest in the fridge. Clays - keep in a dry, dark place. Shelf life is at least 2 years. Herbs All herbs <i>(whole or ground)</i> should be kept in a dark, cool, and dry location. Herbal (liquid) Extracts are created using grain alcohol. The alcohol pulls the constituents (properties) from each herb, root, trunk, leaf, and flower. They have a shelf life of 3-5 years. They can be stored in the refrigerator or a dark, dry place. Other Raw Ingredients - such as Sodium PCA, Honeyquat, Oat Beta Glucan, etc., will all have different shelf lives.
Rose Blossom Hydrosol - is hydrating, soothing, refreshing, cooling, antiaging Rose Stem Cells - are anti-aging, firming, and collagen renewal. Alpine roses are typical Swiss flowers that grow at altitudes of 1500 – 3000 m. In these distinct environments, they must adapt to extreme conditions, including cold, UV exposure, and dryness. PhytoCellTec™ Alpine Rose is based on alpine rose stem cells and captures these characteristics. PhytoCellTec™ Alpine Rose helps to maintain the characteristics of skin stem cells and to protect these precious cells against UV stress.
Benefits:>
Increases skin stem cell vitality Boosts the epidermal regeneration Improves skin barrier function Helps the skin to cope with climate changes Protects skin barrier under harsh environmental conditions Anti-wrinkle effect in the crow’s feet area Visible improvement of skin quality
Elastin - adds elastin to the skin, tightening Oat Beta Glucans - are soothing, calming, anti-aging Progeline™ - biomimetic peptide allows, according to the company, to modulate progerin, to result in a complete remodeling effect and reduction of the appearance of wrinkles and sagging skin. Alpine Rose Active - is the first cosmetic ingredient based on the novel anti-aging concept of senolytics. This mechanism specifically eliminates senescent (aged) cells in the tissue. Senescent cells trigger inflammatory responses and accelerate skin ageing.
Argireline (acetyl hexapeptide-3 or acetyl hexapeptide-8) - prevents dynamic formation.
Argireline affects nerve-to-muscle communication, so muscles can’t adequately contract – fewer muscle contractions result in fewer wrinkles. Argireline is a powerful ingredient that stimulates collagen production, the fundamental building block of skin and hair. Collagen is essential for maintaining elasticity, resilience, and suppleness, providing internal support to keep us flexible and resilient. However, as we age, collagen levels naturally decline, which can begin as early as our mid-twenties. This depletion leads to the formation of wrinkles, sagging skin, and loss of firmness. Syn®-Coll - is a synthetic peptide that stimulates the skin's natural mechanism to produce collagen. It is based on a small peptide developed to reduce any wrinkles. Leucidal SF - (Lactobacilli Fermentation) is a preservative that adds beneficial probiotics to the skin. This preservative does not contain any parabens or formaldehyde releasers All-Trans Resveratrol- extends telomeres in skin DNA, a very effective antioxidant that helps to fight free radical skin damage, packed with vitamins and minerals, skin food in the form of phytonutrients (proanthocyanidin), topically, fights carcinogens, an inhibitor of enzyme oxidative activity SOD (superoxide dismutase) - is an enzyme that quenches excess superoxide radicals and other reactive oxygen species. Hyaluronic Acid ( - is a polysaccharide molecule that offers a viscous matrix to the surroundings and protects cells and their connective tissue. Our eyes have abundant naturally derived hyaluronic acid in our eyeballs. That explains a lot. It is produced throughout our bodies. This product also contains some rich, enticing, and sensual 100% pure essential oils! Pure Essential Oil of Rose, Bulgarian
Pure Essential Oil of Jasmine, Grandiflorum
Frankincense Co2 Extract, Boswellia Carterii
Rose Stem Cell & Peptide Serum - Floral Peptide Infusion for Renewed Skin Vitality
Smells divine and glides across the skin! Delicious!
Ann,
What a perfect way to describe this product.
Keep us updated with your results? It's always nice to know when products do and even when they don't give the expected results.
Markey
R
Rae Lynn Reffruschinni
This was a reorder
I added royal jelly which Had not purchased before.
Hi Rae Lynn
Thank you for the reorder of the Rose Stem Cell Peptide Serum!
It is a staff favorite. Let us know how the royal jelly worked for you.
Markey
G
Gianna
The scent to rival all scent-sations!
It is the most DIVINE of all the serums I've tried at GoW, not only due to it's efficacy, but the scent takes you straight into a rose garden on a mild spring day. Lovely feeling on my skin and to my senses.
Gianna,
What a beautiful way to describe the Rose Stem Cell & Peptide Serum, “a scent to rival all scent-sations”! We’re thrilled you’re loving the Rose Stem Cell Serum, both for its feel and how it transports you.
Thank you for this lovely review!
Markey
A
Alyssa
Indulgent & Essential
The fragrance transports you to a field of blooming roses 🌹 The hydration is incredible! I have a sensitivity to low molecular weight HA. The HA in this serum does not trigger an allergic reaction.
Hi, Alyssa 😊
What a great description! It definitely smells of the natural beauty of roses. How interesting about the hyaluronic acid NOT causing a reaction. I would love to know why. I guess only the skin care goddess knows for sure. --->>> or Jen.
Here's to positive energy in your skin care journey and roses all around.
Markey
T
Terri L Froman
Rose Stem Cell & Peptide Serum
I LOVE this. I have noticed a small change so far, and will continue to use for more results. The smell is delicious! I am so glad I found Garden of Wisdom for my skin care needs (and wants). Most people say I look 10 years younger than I am and in my late 50's, I love the complements. I wish they had a storefront nearby :-) Thank You, Thank You, Thank You.
Terri,
This absolutely makes our day, thank you! We're so happy to hear you're enjoying the Rose Stem Cell & Peptide Serum and already noticing a difference. And those compliments? So well deserved! Radiance at every age is what we’re all about, and we’re honored (honestly, always) to be part of your skincare journey. We’d love to have a storefront near you too, but until then, we’re always just a click away. Thank you again for your kind words and trust in Garden of Wisdom!
Hi MLV
Thank you! for this review.
Keep us updated! It has really helped a lot of customers with body application
to slough off dead skin cells. That sounds kind of gross but very effective. 😉
Immediate results!!!
I had a big weight loss that left my skin with stretch marks and loose skin, i tried so many products and NOTHING compares to this. Within a week, half my stretch marks are faded and my skin tightened and firmed i could actively feel it working after the first use! Only part that is difficult is the ammonia smell but after applying it goes away and doesnt linger so not a big problem for me at all. I love love LOVE this and would recommend! Thank you!
Hi June ⭐️⭐️⭐️
WOW… reviews like this genuinely make us stop in our tracks. Thank you so much for sharing your experience with the FirmAge DMAE Serum.
We know how emotional and frustrating changes in the skin after major weight loss can feel, so hearing that you noticed such a visible difference so quickly is so exciting! We especially appreciate you mentioning the natural DMAE aroma with such honesty and grace. It’s definitely one of those ingredients that prioritizes function over elegance, but we’ve found many customers feel the results make it worthwhile.
We’re beyond grateful you gave it a chance and even more grateful that it’s helping you feel good in your skin again.
With Our Deepest Gratitude, Your Team @ GoW
My favorite serum of all time!! I don't know what took me so long to order this one, but Jen recommended it for hydration, and after finishing up some other (also lovely) GoW serums I finally got myself one of these. It is the most supremely hydrating serum I have ever used. It feels dewy but not greasy, and gives that sinking, unctuous hydration that feels like it really penetrates. I am prone to dehydration, and sometimes it feels like nothing actually soothes it, and products are just sitting on top. Not with Es-care-go!!! I don't even need a cream during the day anymore, which for me is unheard of. Before, without a copious layer or some sort of cream or oil my skin would feel tight. I credit this serum with allowing me to use some retinol again, which is another huge win. Can't live without this one!!!! Thank you GoW!
😙This review absolutely made our day. Thank you for taking the time to share such thoughtful feedback and for trusting Jen’s recommendation.
Hearing that Es-Care-Go Serum helped bring that deep, comfortable feeling of hydration to your skin is exactly what we hoped this serum could offer, especially for skin that feels persistently dehydrated beneath the surface.
We loved reading your description of it feeling dewy yet able to truly sink in, because that balance was incredibly important to us when creating it. Hearing that it helped support your skin enough to comfortably use retinol again is such a huge compliment. It's a great example of the 'proof is in the pudding'. *smiles8
We’re so grateful you’re here with us and beyond happy that this serum found its way into your routine.
˚‧。⋆⋆。‧˚
With appreciation,
Your GoW Crew
Well I can brag about the company all day because my experience is with them have been amazing. They work extra hard to make sure that us the customers are well taken care of in my experience. The prickly pear seed oil seems to be of high quality, silky, and is one the star of my anti-aging ace serum which since purchasing this oil from them has had it come out perfect every time. Great job!!
Derena -`♡´-
This means so much to all of us, thank you. We put a great deal of care into sourcing ingredients that feel beautiful to work with, so hearing that the Prickly Pear Seed Oil has become such a standout in your serum brought a smile to our faces. This is my favorite oil!
We’re also incredibly grateful for your kind words about our team. Taking care of our customers has always been at the heart of what we do, and support like yours genuinely keeps us going.
Wishing you continued beautiful and glowing skin ahead,
Your GoW Crew ⋆ ˚。⋆ ˚。⋆ ˚。⋆ ˚。
This is a great light hand lotion with a great scent that doesn’t irritate my skin
This is a great light hand lotion with a great scent that doesn’t irritate my skin. I wish it was a bit thicker. When I need something heavier, I’ll use the Sinfully Rich Hand Cream.
Thank You 😊❣️for your review.
We completely understand what you mean about it feeling a bit on the thinner side. Over the years, we’ve actually found that many skin products tend to perform best when they’re lighter in texture, as they absorb more comfortably and layer beautifully on prepared skin.
That said, if you prefer a richer feel, we do offer a couple of thicker creams that blend wonderfully with this lotion. A small amount mixed in can create a really lovely texture while still giving you the benefits of both products.
Wishing you well ❤️
Literally the only one I've ever used and I've searched for 30 yrs. Just the best!
Decadent Oat Enriched Emulsion
Teal Schinkel
Works on Melasma!
Nothing has worked so far on my Melasma as well as this. My skin has a glow that it doesn't have when I'm not using. And it's keeping acne at bay. There's a noticeable difference when I don't use this. Don't want to go without.
Clear, Brighten, and Prevent Serum
Rebekah Eustis
great for removing thick sunscreen
This micellar water is the best! I am in the ocean a lot and so wear thick mineral waterproof sunscreen. In the past, trying to get it all off so that my skin didn't break out was always a challenge because the foaming cleansers would dry out my skin. That is why this is a life saver. As another review mentioned, I shake the bottle, pour about a teaspoon or so in my palm and smooth over my face and neck. You can literally see the sunscreen (or make up) melt off. I rinse and then cleanse one more time with the gentle cleansing gel (another winner IMO). My skin is clean but not dry! I love the sensitive formula. Thank you GOW for making such amazing products!
Micellar Cleansing Dew | Sensitive Profile
CT
If I could only use one skincare brand for the rest of my life.
It would truly be garden of wisdom. I started using GOW about 8 or 9 years ago and have never looked back. I haven’t been disappointed by a single product, and I have tried soo many and would bathe in them all daily if I could. several have become staples in my routine, which is about 75% gow products now. The education they provide is genuinely game changing. You not only understand what you’re using and why, but the results are noticeably better than any other store brand skincare I’ve tried.
The company itself is lovely. It’s built on education, research, and experience, not marketing, trends, fake reviews, or the deceptive tactics most skincare brands rely on. Their success comes from a real commitment to honestly informing and educating their community while making truly amazing skincare. Thank you🤍
Garden Of Wisdom Skincare
Margie
Shrinks those bags!
I use this when I’m going out for something special I want to look my best. It really does shrink those puffy tissues around the eyes. It’s a great quick fix item.
Anti-Puffy Eye Serum
Margie
Lovely, soft skin!
Do you know the expression, “If I could bathe in this stuff, I would.”? Well, I do! I know this is an expensive option, but I use this as my body wash for my dry and sensitive body skin. Luckily, a little goes a long way. It’s so gentle and leaves my skin nice and clean, but also super soft at the same time. I use the Honey Butter cleanser on my face and this duo works really well for me.
Oats Milk and Honey Facial Cleanser
Anonymous
C3 Lipid Elixer
I tried this on a whim & I am so happy that I did! My skin is a bit sensitive, as well as very moody. This elixir works with my skin. My skin actually looks better.
Thank you!
C³ Lipid Elixir
Harmony Jensen
Perfect level of moisture.
I use this at night with a few drops of an oil and it’s the perfect level of moisture for my skin, even during winter. Heavy creams cause issue for me and this is perfect.
Decadent Oat Enriched Emulsion (No Essential Oils)
rhonda dawley
Amazingly enough
Amazingly enough... this stuff really seems to be making a difference for the skin under and around my eyes. I'm pleasantly surprised by this eye treatment. I especially love that it is all natural and no silicones, which my skin seems to immensely dislike. I have only been using for a short time but so far am very impressed. I definitely plan to order again!
Beautiful Eyes Serum with ReguAge - for Youthful Eyes
Iryna ivanova
Great experience
Great experience. The company sent me extra oil and even more squalene that I needed as a replacement. They acted quick and very professional. Thanks!r