Our All-Trans Resveratrol is derived from the natural polygonum cuspidatum plant root.
- very effective anti-oxidant which helps to fight free radical skin damage
- packed with vitamins and minerals
- skin food in the form of phytonutrients (proanthocyanidin)
- topically fights carcinogens
- inhibitor of enzyme oxidative activity
- extends the life of telomeres
All-Trans Resveratrol is a phenolic phytoalexin found in grape skin and other plants. It has intracellular antioxidant activity and activates SIRT1, a NAD+-dependent histone deacetylase involved in mitochondrial biogenesis and the enhancement of peroxisome proliferator-activated receptor coactivator-1a (PGC-1a) and FOXO activity. The anti-diabetic, neuroprotective and anti-adipogenic actions of resveratrol may be mediated via SIRT1 activation. That was a mouthful!!
You may have heard, that the incidence of heart disease in France is far lower than in the U.S. Scientists spent a long time trying to figure out how that could possibly be when the traditional French diet – lots of cheese, bread, sauces, and wine with every meal - which includes pretty much everything we’re advised not to eat. After much research, they think they’ve found the secret in All-Trans Resveratrol - an excellent anti-aging ingredient you might want to add to your skin care routine.
What is the magic ingredient? It’s called All Trans-Resveratrol. This is found in many red wines, and is an antibiotic produced by plants when under attack by bacteria, fungi and other substances that can cause disease or illness. Although the formal research has been conducted primarily in test tubes and on animals, All-Trans Resveratrol has reportedly been effective in fighting viruses, inflammation, cancer and neurological diseases. It is also being touted for its anti-aging effects.
While antibiotics are not new in the skin care field for some skin diseases, it’s unusual to think that an antibiotic can also be effective when it comes to aging. However, many scientists now believe that a host of degenerative diseases are actually caused by bacteria and inflammation. That certainly is true of some skin conditions, which is one of the reasons for the popularity of antibacterial skin care products.
In a recent study, the antioxidant strength of 1% All-Trans Resveratrol was compared to that of 1% Idebenone. Idebenone is a powerful pharmaceutical antioxidant. Its benefits include shielding the skin from environmental damage, improving the appearance of fine lines and wrinkles, reducing dryness, and smoothing skin texture. The results of the study revealed that All-Trans Resveratrol had a stunning 17-fold greater antioxidant capacity than Idebenone! All-Trans Resveratrol is also able to form soluble, complex molecules with certain metal ions, inactivating the ions so they cannot produce free radical formation. This action, in combination with its powerful antioxidant capability, makes All-Trans Resveratrol highly effective in combating the damaging effect of free radicals that leads to skin aging. All-Trans Resveratrol is also reported to stimulate healthy cell proliferation as well as collagen synthesis by protecting the dermal matrix from harmful enzymes and improving the function of fibroblasts that create healthy collagen.
The Role of Telomeres - What is a Telomere?
From Wikipedia: A telomere (/ˈtɛləmɪər/ or /ˈtiləmɪər/, from Ancient Greek: τέλος, romanized: télos, lit. 'end' and Ancient Greek: μέρος, romanized: méros, lit. 'part') is a region of repetitive nucleotide sequences associated with specialized proteins at the ends of linear chromosomes. Although there are different architectures, telomeres in a broad sense, are a widespread genetic feature most commonly found in eukaryotes. In most, if not all, species possessing them, they protect the terminal regions of chromosomal DNA from progressive degradation and ensure the integrity of linear chromosomes by preventing DNA repair systems from mistaking the very ends of the DNA strand for a double strand break.
What can All-Trans Resveratrol do to help with Telomere function? Telomeres are important because they extend the life of skin cells. Unfortunately as we age we accumulate toxins, free radicals and chemicals in our skin which damage the telomeres causing the telomeres to shorten. All-Trans Resveratrol helps extend these telomeres by increasing telomerase activity in the skin.
Studies have shown that All-Trans Resveratrol significantly increases the telomerase activity by increasing the expression of the catalytic subunit of human telomerase reverse transcriptase (hTRET) in a dose-dependent manner. Long story short - All-Trans Resveratrol has the potential to be a skin saving ingredient!
Additional Reading - Article
Extending Lifespan - Telomere Theory of Aging
The following products feature All-Trans Resveratrol
CoQ10 AntiAging Serum W All-Trans Resveratrol
Progeline Peptide Repair Serum
Advanced Telomere Repair and AntiAging Serum
Concord Grape AntiOxidant Serum
Adipofill Natural Wrinkle Filler Serum