There are three processes in face aging: cellular aging, cutaneous aging, and structural aging, which is where Adipofill™ fits in. Structural aging decreases adipose tissue, which is responsible for facial plumpness. As we age, this "fat pad progressively melts due to a disturbance of adipocyte metabolism, which causes the appearance of deep nasolabial folds, saggy jowls and hollowness under the eyes." Adipofill™ was engineered to mimic lipofilling results (such as those used in plastic surgery) by activating hypoxia-inducible factor (HIF)-1-alpha, a transcription factor, stimulating adipocyte anabolism and decreasing fatty acids release, ultimately reducing nasogenian wrinkles for a plumper and youthful look, and offering facial rejuvenation.
NOTE: A couple of our customers developed a rash with this serum followed by tiny bumps. Double-check to make sure the ingredients are adaptable to your skin profile.
Method of Application Apply several drops to targeted areas two times per day after cleansing and toning. Let dry and continue with layering your serums or adding oil and/or cream if deemed necessary to seal these important actives into the skin.
Shelf Life and Storage Information for Products and Ingredients
Finished Products generally don't need to be refrigerated as they are preserved, but you can refrigerate them to extend their shelf life. The shelf life for most products is 9-12 months. Vitamin C Serum(s) and VitaResurface products should continually be refrigerated to extend their shelf life.
Sample Sizes do have a shorter shelf life (generally 3-6 months) , and items in jars can dry up quicker than this if the lid is not tightened well enough (except for our Vitamin C Serums - use within 90 days).
Please keep your products out of humidity, heat, direct light and in a dark cabinet when possible.
Exfoliating Acid products have a shelf life of 9-12 months. The only things we don't suggest refrigerating are the Mandelic Acid Serums or Salicylic Acid Serums, as they can crystallize in the refrigerator. If this happens, you can set the product into a hot water bath to see if the crystals will dissolve.
Additional Items That Require Refrigeration and/or Kept in the Dark
Hydrosols - remove 1 ounce of hydrosol and add it into a separate, sterilized spray bottle and spritzer. Keep the larger bottle in the refrigerator. Carrier Oils - generally, you can refrigerate all carrier oils, although some very rich oils will solidify. This is fine. All you have to do is take it out, warm it up at room temperature and it should liquefy. If not, set the bottle in a hot water bath and occasionally shake the bottle, which will hopefully turn into a liquid. ^There are some oils with a super long shelf life, like Coconut Cream and Jojoba Oil. Refrigeration is not necessary, but it surely won't hurt. Essential Oils - essential oils are best stored in a cool, dark place. Co2 Extracts - these should continually be refrigerated. Butters - we suggest refrigerating our "skincare' butters. You can remove what you need and keep the rest in the fridge. Clays - keep in a dry, dark place. Shelf life is at least 2 years. Herbs - all herbs (whole or ground) should be kept in a dark, cool and dry location. Herbal (liquid) Extracts - these are created using alcohol. The alcohol pulls the constituents from each herb—root, trunk, leaves, and flowers. Extracts have a shelf life of 3-5 years. They can be kept in the refrigerator (or a dark DRY place) Other Raw Ingredients - i.e., Sodium PCA, Honeyquat, Oat Beta Glucan, etc. will all have a different shelf life.
Glycoproteins aids in the cellular repair process, boosts the skin's oxygen content, increases the energy level of skin cells by enhancing the production of energy-rich adenosine triphosphate, high in polysaccharides which allows for extra hydration to the skin. Glycoproteins boost the skin's oxygen content, increase the cellular respiration capacity, and increase the energy level of skin cells by enhancing the production of energy-rich adenosine triphosphate (ATP). Glycoproteins also have moisturizing properties due to their content of water-binding polysaccharides.
Adipofill™(formulated with the strongest percentage recommended by manufacturer) a patented L-ornithine amino acid encapsulated in an Ionosome. Adipofill™ reproduces lipohormesis phenomenon by activating HIF-1α gene expression and related genes involved in the global adipocyte anabolism. Adipofill™ therefore mimics lipofilling result in a non-surgical way. By acting on adipose tissue growth with a bio-contolled and non-invasive mechanism, Adipofill™ clinically reverses the age-related signs of lipoatrophy. Adipofill™ is thus an innovative, sophisticated and high-tech ingredient that fights the aging process for a plump and youthful look.
Astaxanthin naturally-occurring carotenoid found in algae, anti-oxidant, anti-inflammatory
Resveratrol functions (in plants) as a phytoalexin, a substance produced by plants that can inhibit the growth of infecting fungi or other pathogens. Resveratrol presents itself with antiviral, antioxidant, anti-inflammatory, and neuroprotective activities which fights the degradation of cell functioning to fight the free-radicals