Sometimes your skin is not dry, not oily, not even reactive... it is simply overwhelmed. It stops responding the way it used to. It looks a little more tired, a little less even, a little harder to settle. This is where Revitalize Your Skin Serum with Neurophroline™ begins.
This silky, lightweight serum was created for skin that is carrying the effects of daily stress. Not to force change, but to gently support a calmer, more balanced appearance. Skin is left looking more even, more rested, and more at ease.
At the center of this formula is Neurophroline™, a wild indigo seed extract chosen specifically for its ability to help reduce the visible effects of stress on the skin by reducing cortisol production locally in the skin cell. Rather than pushing the skin harder, it works in a quieter way, supporting a more refreshed, balanced complexion over time.
We paired it with Oat Beta Glucan, Thermo-stressine, Superoxide Dismutase, and other carefully chosen ingredients that help comfort the skin and defend against visible environmental strain.
This is not about pushing the skin harder. It is about helping it find its way back to balance.
Key Benefits
➜ Helps reduce the visible effects of daily skin stress
➜ Supports a calmer, more balanced-looking complexion
➜ Helps improve the appearance of uneven tone and fatigue
➜ Lightweight hydration without heaviness or buildup
➜ Supports skin exposed to environmental and emotional stress
Why It Feels Different
When skin is under ongoing stress, it does not always react loudly. Instead, it can begin to look duller, feel less comfortable, or lose some of its natural balance. This formula was designed with that in mind.
Neurophroline™ helps target the visible effects of stress on the skin, while Oat Beta Glucan helps soothe and support the skin barrier. Thermo-stressine helps support skin exposed to changing environmental conditions, and Superoxide Dismutase offers antioxidant support to help defend against visible oxidative stress.
Together, these ingredients create a serum that feels light, calm, and supportive, especially for skin that needs less pressure and more consistency.
Method of Application
Apply a small amount to clean skin after your water-based layers and before heavier serums, oils, or creams. Gently smooth over the face, focusing on areas that appear tired, uneven, or stress-worn. Use morning, evening, or both.
Featured Ingredients
➜Neurophroline™ – is a wild indigo seed extract that helps stressed skin calm down. Skin cells can produce cortisol locally in response to stress, and when cortisol stays elevated it can show up as redness, dullness, dehydration, and a more reactive barrier. Neurophroline is designed to help reduce cortisol production in skin cells while also encouraging the release of a calming neuropeptide (beta-endorphin), which supports a more balanced, refreshed-looking complexion over time.
➜Oat Beta Glucan – Helps soothe and support the skin barrier, contributing to a calmer feel.
➜Thermo-stressine – Helps support skin exposed to environmental stress and fluctuating conditions.
➜Superoxide Dismutase (S.O.D.) – An antioxidant enzyme that helps defend against visible oxidative stress.
Technical Notes
Neurophroline™ is derived from Wild Indigo (Tephrosia purpurea). This specialized extract contains naturally occurring sugars, including stachyose and ciceritol, and has been studied for its ability to help visibly improve skin tone and reduce the appearance of stress-related skin fatigue.
Shelf Life and Storage Information for Our Products and Ingredients
Finished Products - generally don't need to be refrigerated as they are preserved, but you can refrigerate them to extend their shelf life. The shelf life for most products is 9-12 months. Vitamin C Serum(s) and VitaResurface products should continually be refrigerated to extend their shelf life. Sample Sizes - do have a shorter shelf life (generally 3-6 months), and items in jars can dry up quicker than this if the lid is not tightened well enough (Vitamin C Serums - use within 90 days).
Please Keep Your Products Out of Humidity, Heat, Direct Light and in a Dark Cabinet When Possible
Exfoliating Acid - products have a shelf life of 9-12 months. The only things we don't suggest refrigerating are the Mandelic Acid Serums or Salicylic Acid Serums, as they can crystallize in the refrigerator. If this happens, you can set the product into a hot water bath to see if the crystals will dissolve.
Additional Items That Require Refrigeration and/or Kept in the Dark
Hydrosols and Distillates - remove 1 ounce of hydrosol and add it to a separate, sterilized spray bottle and spritzer. Keep the larger bottle in the refrigerator. Carrier and Exotic Oils - generally refrigerate all carrier oils, although some very rich oils will solidify. This is fine. All you have to do is take the oil out, warm it up at room temperature, and it should liquefy. If not, set the bottle in a hot water bath and occasionally shake the bottle, which will hopefully turn into a liquid. Some oils, like coconut cream and jojoba oil, have a super long shelf life.
Refrigeration of The Following Ingredients is Not Necessary, But it Won't hurt
Essential Oils - essential oils are best stored in a cool, dark place. Co2 Extracts - these should continually be refrigerated. Butters - we suggest refrigerating our "skincare" butters. You can remove what you need and keep the rest in the fridge. Clays - keep in a dry, dark place. Shelf life is at least 2 years. Herbs All herbs <i>(whole or ground)</i> should be kept in a dark, cool, and dry location. Herbal (liquid) Extracts are created using grain alcohol. The alcohol pulls the constituents (properties) from each herb, root, trunk, leaf, and flower. They have a shelf life of 3-5 years. They can be stored in the refrigerator or a dark, dry place. Other Raw Ingredients - such as Sodium PCA, Honeyquat, Oat Beta Glucan, etc., will all have different shelf lives.
Shipping Transit Note: Some customers have asked whether products can be affected by time in transit, especially during warmer months. Our products are formulated and preserved to remain stable during normal shipping times and should not spoil simply from being in transit.
That said, if you are concerned about heat exposure, you are welcome to add an ice pack to your order for extra peace of mind. Click here to add an ice pack.
Spring Water hydrating and helps prepare the skin to accept active ingredients Liposomes (phospholipids) penetration enhancer and extremely hydrating Leucidal SF (Lactobacillis Ferment) gentle preservative without parabens or formaldehyde releasers Neurophroline this exclusive extract has demonstrated its unique biological capabilities to break down the cortisol production by skin cells, activate the release of a natural calming neuropeptide acting to reduce redness, and enhance the overall appearance of the skin. Thermostressine® (tetrapeptide)this tetrapeptide increases the skin's tolerance to jet-lag and other daily lifestyle stresses. The proteotoxic stress is well controlled and damage prevented. Oat Beta Glucans are being studied for their potential immunomodulatory effects, anti-tumor properties, and stimulation of collagen deposition. Oat Beta Glucans have amazing healing properties.
Hyaluronic Acid (high molecular weight)Hyaluronic acid is a natural polysaccharide (large sugar molecule) that occurs in various tissues (skin, synovial fluids of joints, connective tissues).
Hyaluronic Acid(super low molecular weight)hyaluronic acid (sodium hyaluronate) is a natural polysaccharide (sugar) that occurs in body tissues including the skin providing hydration, stability, lubrication. This super low-molecular-weight form is made by enzymatically cleaving high-molecular weight hyaluronic acid into small fragments.
Dehydroxanthan Gumis obtained from fermented polysaccharides.This ia natural thickener. AllTrans ResveratrolAllTrans-resveratrol is a naturally occurring compound in certain plants, particularly grapes and red wine. It has been of interest in skincare and cosmetics due to its potential antioxidant and anti-aging properties. When applied topically to the skin, trans-resveratrol can exhibit several beneficial properties like antioxidant protection, anti-inflammatory, skin brightening, UV protection, collagen production and really keeps the skin hydrated. Apple Polyphenols are natural compounds found in apples, particularly in the skin and seeds of the fruit. They are a type of phytochemical, which means they are plant derived. Apple polyphenols, when used in topical applications, offer antioxidants, UV Protection, anti-inflammatory effects, they improve skin hydration while boosting collagen production. Yes, they are this good. Sclerotium Gum is a naturally derived, gel-like polysaccharide (sugar-based) thickener. Super Oxide Dismutase (S.O.D.) the highly purified superoxide dismutase made from Saccharomyces cerevisiae for skin care products. Offering anti-aging and skin-whitening properties while providing potent antioxidant effects inhibiting free radical formation.
I really love this product, I am 44 and it has helped the area around my eyes and around my mouth. My skin appears firmer. Only problem is it is always sold out when I go to order more!
Thank you ❀ we are so happy the serum is helping your skin. We apologize for the out-of-stock issue and recommend signing up for restock notifications to be the first to know when it's available again.
Again, ᵗʰᵃᶰᵏᵧₒᵤ! ✌︎㋡ for the kind review. I love this serum myself.
Have a happy week ahead,
Markey 🌸🌸🌸
E
Erika Davies
lovely tool in fighting signs of aging
This serum is a lovely tool in fighting signs of aging cause by lifes little stressors :)
Thank you, Erika.
You are adorable. We are always happy to hear when a product shows the results
one is hoping for.
Thank you for the video!
Markey ˚⊱⊰˚
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Anonymous
Love it!
I love this product & so does my skin! For me, that is a huge blessing.
Hi Elayne!
Thank you for mentioning this product. It doesn't get enough ❤️.
Wishing you the best, as always, with your skincare journey.
Markey and Your GoW Crew of Lovlies.
˖˳·˖ ִֶָ ⋆͙⋆ ִֶָ˖·˳˖ ִֶָ
R
Rachel
Staple!!
Love love all GoW products I've tried, but this one was particularly interesting because of the Cortisol component! My skin has been a challenge the last 10 years and a lot of that was likely due to stress and hormones. In the last few years, things seemed to have leveled out but I still need support of course. I really do believe in a week or so I saw results from this serum. My skin is happy and hydrated! About to reorder my 2nd bottle :)
This is such a thoughtful review, and we're SOO happy for your results! Thank you so much :)
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Frances S
Amazing product
I used this serum for the first time this week and I swear my skin immediately felt immediate relief. My skin actually feels satiated when I apply the serum. It is more even and glowing. I’m obsessed and hope this product is restocked asap. Thank you garden of wisdom!!!
Frances! I couldn't agree more! We tested this for awhile before releasing it and this product really is a game changer especially for those of us who find it more challenging to keep our skin hydrated and beautiful.
Thank you for the wonderful review, we always appreciate reviews.
Markey :-D
Love this new formula with the frankincense so much that I had to get the larger size! I've been using hyaluronic acid plus squalane oil as a moisturizer because I couldn't find a moisturizer that didn't irritate my face or make it drier. I like that this balm has a few simple amazing ingredients with no added fragrance or preservatives. It doesn't irritate my skin or flare up my rosacea. This is the only moisturizer that has actually provided hydration for my skin. I use a small dab at night so the product lasts for many months and leaves my skin with a healthy glow.
Hi Teresa, your review truly makes us smile. I always read reviews out loud and I know the staff here is very proud of their work. Knowing this facial balm works so well for your skin is awesome to hear! Thank you for sharing your experience and for being a loyal customer.
Wishing you continued glowing skin!
Your GoW Team ˖˳·˖ ִֶָ ⋆🪷⋆ ִֶָ˖·˳˖ ִֶָ
This is still my favourite cleanser after many many bottles! It never fails. So gentle it Doesn’t leave my skin dry yet still is cleansing and refreshing - my go to!
Hi Cortney, we're thrilled to hear it's still your favorite! Thank you for your continued trust and support. I so wish there was a way to spread the word for this kind to the skin cleanser. :-)
Thank you so very much.
Markey ᵗʰᵃᶰᵏᵧₒᵤ! ✌︎㋡
I really love this product, I am 44 and it has helped the area around my eyes and around my mouth. My skin appears firmer. Only problem is it is always sold out when I go to order more!
Thank you ❀ we are so happy the serum is helping your skin. We apologize for the out-of-stock issue and recommend signing up for restock notifications to be the first to know when it's available again.
Again, ᵗʰᵃᶰᵏᵧₒᵤ! ✌︎㋡ for the kind review. I love this serum myself.
Have a happy week ahead,
Markey 🌸🌸🌸
Honestly so impressed with this gel. Very hydrating and non irritating for sensitive skin.
Hi there! We're so happy to hear you're impressed with the gel and that it works well for your sensitive skin. This is always nice to hear!
Thanks for sharing your experience!
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In my 70yrs still having breakouts, trying EVERYTHING!!! Prescription and over the counter. This is the 1st product I’ve ever used, that really works!! Will definitely reorder and recommend!
Christine
Thank you so much for sharing your experience with this! Since I just turned 70 myself I know how frustrating our skin can behave. I am (we are) truly excited for your skin and your heart. ;-) Your outcome will hopefully help many others with their frustrating skin issues.
Wishing you all the best on your skin's journey to health.
Markey ✺◟(👁 ͜ʖ👁)◞✺
Love this new formula with the frankincense so much that I had to get the larger size! I've been using hyaluronic acid plus squalane oil as a moisturizer because I couldn't find a moisturizer that didn't irritate my face or make it drier. I like that this balm has a few simple amazing ingredients with no added fragrance or preservatives. It doesn't irritate my skin or flare up my rosacea. This is the only moisturizer that has actually provided hydration for my skin. I use a small dab at night so the product lasts for many months and leaves my skin with a healthy glow.
This is still my favourite cleanser after many many bottles! It never fails. So gentle it Doesn’t leave my skin dry yet still is cleansing and refreshing - my go to!
Soothing Cleansing Gel 100% Soap Free
Anonymous
Awesome
I really love this product, I am 44 and it has helped the area around my eyes and around my mouth. My skin appears firmer. Only problem is it is always sold out when I go to order more!
Neurophroline® Skin Stress Serum
Anonymous
Honestly so impressed with this gel
Honestly so impressed with this gel. Very hydrating and non irritating for sensitive skin.
Encapsulated Glacier Water Hydrating Gel
Christine Rabena
A product that really works!
In my 70yrs still having breakouts, trying EVERYTHING!!! Prescription and over the counter. This is the 1st product I’ve ever used, that really works!! Will definitely reorder and recommend!
Thanakha Blemish Clearing Tonic
Sarah Dawson
Such a lovely oil!
Such a lovely oil!
It glides on so smoothly, feels like a substantial oil without leaving me greasy, and I love that it has a mild color so I can put it on directly. I live in the Southwest so it’s so fun to use the oil from a plant that I see around me all the time! Thank you Garden of Wisdom for being the oasis in the desert and delivering such wonderful products!
Prickly Pear Seed Oil - The Secret to Timeless Radiance
Karissa Michitsch
the product that gave me my skin back!
if i could give this serum more than five stars, i would.
i developed rosacea out of nowhere after never really having skin issues before. suddenly my skin was red, bumpy, dry, dehydrated and unbelievably reactive. i tried so many products that were marketed as natural, sensitive-skin friendly or rosacea-safe, and NOTHING worked. every new product seemed to give me a brand-new version of a reaction.
then i had a consultation with jennifer. garden of wisdom offers consultations for new customers, and i cannot recommend doing one enough. jennifer was incredible. she helped me put together a very simple routine using this serum, their soap free cleanser, aloe as a toner and evening primrose oil. she also talked to me about supporting my skin internally, which i really appreciated. it felt like she was looking at the bigger picture instead of just trying to sell me another topical product.
more than that, she was kind, supportive and genuinely gave me hope during a time when i was feeling incredibly discouraged about my skin.
and boy did she deliver.
i used the cleanser and oat enriched facial serum and woke up the NEXT MORNING with skin that felt smooth, calm and unreactive. i genuinely could not believe it.
and it wasn't a fluke. over time, everything improved - the redness, the little bumps and texture, the dryness, the hydration, the flushing, the way my skin responded to heat, and even how quickly it recovered when something did make it reactive. my skin didn't just look better. it started to feel healthier, stronger and more resilient.
the serum itself feels like a pretty normal serum on the skin. i will warn you that it has an interesting smell, but you get over that very quickly once you realize how magical the stuff inside the bottle is. most importantly, it has never - literally NEVER - irritated my skin. no burning, stinging, redness, bumps or mystery reaction of the week.
i've now been using it for almost three months, and the difference in my skin is enormous. instead of constantly reacting to something new, my skin just kept getting healthier.
the craziest part is that at this point, i pretty much forget that i even have rosacea. when i think back to how reactive, uncomfortable and unpredictable my skin felt just a few months ago, i can't believe i'm saying that.
after months of feeling like my own face had suddenly become something i couldn't understand or control, garden of wisdom gave me my skin back.
i never want to be without this serum. ever.
Oat Enriched Facial Serum
Karissa Michitsch
simple, gentle, and somehow life-changing!
i developed rosacea seemingly out of nowhere after having basically no skin issues my entire life. suddenly i had redness, bumps and texture, dryness, a completely compromised skin barrier, and it felt like EVERYTHING i put on my face caused some new version of a reaction. i had already used natural/holistic skincare for years, and even products marketed as "sensitive" or "rosacea-safe" were not working for me.
then i found garden of wisdom.
this cleanser is definitely a different experience from a traditional face wash (read the directions!) but i got used to that almost immediately. and honestly, i would wash my face standing on my head at this point if that's what it took to keep my skin this happy.
my skin has never once reacted to it. it feels completely calm, clean and refreshed afterward, but NEVER stripped or tight, which was especially impressive considering what a disaster my skin barrier was when i started using it.
i began using this cleanser at the same time as the oat enriched facial serum, so i can't honestly tell you which product deserves more credit. what i can say is that my skin changed almost literally overnight. i woke up with smoother, calmer, more hydrated skin, and over the weeks that followed my redness, texture, hydration and overall skin health continued to improve. i kept waiting for the other shoe to drop because it genuinely felt too good to be true. it never did.
i've now been using this for almost three months, and the change is kind of unbelievable. at this point, i pretty much forget that i even have rosacea. considering how much my skin was affecting my day-to-day life when this first started, that feels enormous.
i truly believe that replacing everything that may have been irritating or inciting my skin with something this gentle played a huge role in allowing my skin to calm down and become so much more resilient.
if you wear makeup, i would pair it with garden of wisdom's micellar water, which i also love.
finding a cleanser that thoroughly cleans reactive, rosacea-prone skin without making it even remotely angry should not feel this miraculous, but after everything i tried before this, it absolutely does.
Soothing Cleansing Gel 100% Soap Free
Elizabeth Kankam
The best!
I got this product last week but finally used it last night. I woke up this morning so delighted that I had to rush to leave a review. This is from someone who barely leaves reviews. I’ve always been texture and hyperpigmentation prone as a person of color. I recently started using tretinoin but even the 0.025% makes my skin flaky and irritates my skin barrier all the time. So I started looking for a gentler retinol option but every product I found had ingredients that will either clog my pores or not work at all till I finally found GOW. I was immediately attracted to the simple ingredients list. I was a bit worried about my skin barrier so last night, I used a moisturizer as a buffer before applying the serum. I woke up to see a radiant skin with my pores looking visibly clearer. This product will forever be a staple in my routine! This and the clear,brighten and prevent serum! Please never discontinue this product.
Vita ReSurface™ Serum All-Trans Retinol
Anonymous
Little bottle
Little bottle. Big results.
This stuff is the bomb! It showed results the very next day. My blemish was much smaller on day 2 and gone on day 3. Used it am and pm. Just a very tiny dab.
