Turn Back the Clock on Aging Unlock the secret to youthful, plump skin with Adipofill™ Natural Wrinkle Filler Serum – the Advanced Anti-Aging Solution to Achieve Youthful Skin. Specially designed to combat the three primary processes of facial aging - cellular, cutaneous, and structural, this innovative serum specifically targets structural aging, which leads to a decrease in adipose tissue and the visible loss of facial fullness.
As we age, our facial fat pads gradually diminish due to disruptions in adipocyte metabolism, leading to deep nasolabial folds, sagging jowls, and hollows under the eyes. Adipofill™ Natural Wrinkle Filler Serum mimics the rejuvenating effects of lipofilling, a procedure often used in plastic surgery, by activating hypoxia-inducible factor (HIF)-1-alpha, a critical transcription factor. This activation stimulates adipocyte anabolism and reduces fatty acid release, helping to visibly plump and firm the skin while significantly reducing nasogenian wrinkles for a naturally youthful appearance.
An Innovative, Non-Surgical Solution
Harnessing the lipo hormesis phenomenon, Adipofill™ Natural Wrinkle Filler Serum enhances HIF-1α gene expression and related genes associated with adipocyte growth. This leads to a non-invasive, bio-controlled rejuvenation of facial structure, delivering surgical-like results without the need for injections or incisions. Supported by clinical studies, this serum offers a breakthrough approach to age-related facial volume loss, making it a valuable addition to any advanced anti-aging regimen.
Key Ingredients for Total Skin Rejuvenation
Anemarrhena Asphodeloides Root Extract - Promotes skin plumping for a fuller appearance. Panthenol (Vitamin B5) - A deeply penetrating moisturizer that soothes, heals, and encourages cell regeneration. Glycoproteins - Boost oxygenation, energy levels, and hydration while aiding cellular repair. Adipofill™ (L-ornithine in liposomes) - Clinically proven at the manufacturer's highest recommended concentration to visibly fill and lift aging skin. Aspen Bark Extract - A natural exfoliant and antibacterial agent that preserves skin health. Astaxanthin - A potent antioxidant that combats oxidative stress and inflammation. Resveratrol - A powerful free radical fighter that supports overall skin vitality and longevity.
Experience Youthful, Plump Skin
Reclaim youthful vibrance with Adipofill™ Natural Wrinkle Filler Serum – the Advanced Anti-Aging Solution to Achieve Youthful Skin. Achieve firmer, smoother, and fuller skin without invasive procedures, only the pure power of science-driven skincare. Say goodbye to deep wrinkles and sagging skin and welcome the rebirth of your natural radiance!
NOTE: While this formula delivers outstanding results for many, a few customers have reported mild irritation, including a rash and tiny bumps. We recommend reviewing the full ingredient list to ensure compatibility with your skin profile before use.
Shelf Life and Storage Information for Our Products and Ingredients
Finished Products - generally don't need to be refrigerated as they are preserved, but you can refrigerate them to extend their shelf life. The shelf life for most products is 9-12 months. Vitamin C Serum(s) and VitaResurface products should continually be refrigerated to extend their shelf life. Sample Sizes - do have a shorter shelf life (generally 3-6 months), and items in jars can dry up quicker than this if the lid is not tightened well enough (Vitamin C Serums - use within 90 days).
Please Keep Your Products Out of Humidity, Heat, Direct Light and in a Dark Cabinet When Possible
Exfoliating Acid - products have a shelf life of 9-12 months. The only things we don't suggest refrigerating are the Mandelic Acid Serums or Salicylic Acid Serums, as they can crystallize in the refrigerator. If this happens, you can set the product into a hot water bath to see if the crystals will dissolve.
Additional Items That Require Refrigeration and/or Kept in the Dark
Hydrosols and Distillates - remove 1 ounce of hydrosol and add it to a separate, sterilized spray bottle and spritzer. Keep the larger bottle in the refrigerator. Carrier and Exotic Oils - generally refrigerate all carrier oils, although some very rich oils will solidify. This is fine. All you have to do is take the oil out, warm it up at room temperature, and it should liquefy. If not, set the bottle in a hot water bath and occasionally shake the bottle, which will hopefully turn into a liquid. Some oils, like coconut cream and jojoba oil, have a super long shelf life.
Refrigeration of The Following Ingredients is Not Necessary, But it Won't hurt
Essential Oils - essential oils are best stored in a cool, dark place. Co2 Extracts - these should continually be refrigerated. Butters - we suggest refrigerating our "skincare" butters. You can remove what you need and keep the rest in the fridge. Clays - keep in a dry, dark place. Shelf life is at least 2 years. Herbs All herbs <i>(whole or ground)</i> should be kept in a dark, cool, and dry location. Herbal (liquid) Extracts are created using grain alcohol. The alcohol pulls the constituents (properties) from each herb, root, trunk, leaf, and flower. They have a shelf life of 3-5 years. They can be stored in the refrigerator or a dark, dry place. Other Raw Ingredients - such as Sodium PCA, Honeyquat, Oat Beta Glucan, etc., will all have different shelf lives.
Spring Water - hydrating, natural solvent Anemarrhena Asphodeloides Root Extract - skin plumping Panthenol B-5 - penetrating moisturizer, soothing, healing, encourages cell regeneration Glycoproteins - aids in the cellular repair process, boosts the skin's oxygen content, increases the energy level of skin cells by enhancing the production of energy-rich adenosine triphosphate, high in polysaccharides which allows for extra hydration to the skin. Glycoproteins boost the skin's oxygen content, increase the cellular respiration capacity, and increase the energy level of skin cells by enhancing the production of energy-rich adenosine triphosphate (ATP). Glycoproteins also have moisturizing properties due to their content of water-binding polysaccharides. Adipofill™ - (we formulate with the strongest percentage recommended by the manufacturer) a patented L-ornithine amino acid encapsulated in an Ionosome. is thus an innovative, sophisticated, and high-tech ingredient that fights the aging process for a plump and youthful look. Aspen Bark Extract - preservative, gentle exfoliator, anti-bacterial Astaxanthin - naturally-occurring carotenoid found in algae, anti-oxidant, anti-inflammatory Resveratrol - functions (in plants) as a phytoalexin, a substance produced by plants that can inhibit the growth of infecting fungi or other pathogens. Resveratrol presents itself with antiviral, antioxidant, anti-inflammatory, and neuroprotective activities which fights the degradation of cell functioning to fight the free-radicals Xanthan Gum - natural thickener
Cynthia
So far, it seems to be plumping deep wrinkles. - Adipofill™ Natural Wrinkle Filler Serum.
Please keep us updated here or privately if you wish.
Thank you!
V
Valerie
Great serum!
I have had great luck with Adipofil! It has definitely added volume to my face. I use this serum every evening. As we age, we noticeably lose volume in our face and I will use anything that might help to maintain it!
Thank you for the review, Valerie.
We know it takes time from your busy day to list reviews and yours are
dearly appreciated.
Your GOW team :-D
M
Mary Gleason
Love item
Only using for a short time so far but feel Im already noticing positive results and seem to notice less hollowing in areas of concern. Very pleased! Am gonna keep using. Great product!
Mary,
Thank you for this review! This is one product that will work given time depending on how long the customers have had to deal with the 'hollowing'.
It's always important that customers are able to read others results.
Again, thank you!
Markey
A
Anne
A great addition
I enjoyed using this product. It plumped out fine lines and added in other problem areas. I love trying things I don’t see in other skin care lines. Thanks gow for something new.
I'm not sure that I actually have rosacea, but my cheeks tend to get red in response to many products. Once I finally realized this I've been careful to keep retinol away from them and use this instead. I have so much less flushing and also a very smooth texture on my cheeks now. A tiny drop is all I need for the small area, so the 0.5 oz bottle is lasting forever. Thank you GOW for making so many products that I can really customize and adapt my routine! I wrote somewhere else in a review that my bathroom drawer looks like I robbed the warehouse - I just love so many of these products and somehow find the time and space on my face to use them all!!
Hello Devotee 😉
Thank you for sharing your experience. We are so glad this has helped reduce redness and keep your skin smooth and comfortable. It is wonderful to hear that you can tailor your routine with products that work best for you. Your kind words and loyalty mean so much to us, and your bathroom drawer description made us smile.
Your GOW Team (with love)
Thank You 😊❣️
I've used this on and off for years, and in the past few months have been using 2-3x per week. Whenever my skin is a little flaky or rough, 10 minutes of this mask makes me all silky and smooth. It also seems like it prepares my skin well for other products to sink in. I've gotten into a habit of a quick lukewarm water rinse in the morning (or a longer one if I've used retinol), then applying a layer of this for 20 minutes or so while I do household chores. I rinse it off in the shower and then continue my routine and it really seems to brighten and refine my skin. It's especially amazing for blocked pores or tiny blemishes - I feel like I can see an immediate difference after just a few minutes. Can't live without this one, can't live without GOW!!
Devotee
Thank you for such a thoughtful and detailed review. We love hearing how you have made the UnCork My Pores Cabernet Mask part of your routine and that it has helped keep your skin smooth, bright, and refined. It is wonderful to know it works so well for blocked pores and minor blemishes, and that you see such an immediate difference. We truly appreciate your loyalty and your kind words about GOW.
Feedback like yours inspires us every day. NOTE: this is one of my favorite products as well.
Markey
Got this as a free sample (I LOVE the samples!!!) and will re-order this one. Nice silky texture and doesn't pill when layered. I've been using this every morning and every other night (some nights I use GOW retinol cream alone) mixed with the bakuchiol oil. I really like a serum to help make oils glide on and not get too goopy. I let the combo sink in for a few minutes, then apply sunscreen in the morning, and sometimes another oil at night. Thanks to all of my GOW products my skin does not look its 40 years, and still feels quite plump and thick. Thank you!!! xoxoxoxo
xoxoxoxo back at you!
We are delighted to hear that the Progeline Peptide Repair Serum has integrated so seamlessly into your morning and evening routines. The silky texture and compatibility with both bakuchiol oil and retinol cream are exactly what we aimed for (compatibility with our products) when formulating this serum. Knowing it helps enhance, improve the glide, and supports your skin’s firmness is incredibly rewarding for us.
We appreciate your thoughtful feedback and are so glad the sample led you to a new favorite. YOUR GoW Team
I've taken a years-long break from acids after over-using mandelic acid and causing some barrier disruption. Thanks to many other GOW products I was getting along well, but still dealing with some tiny blocked and enlarged pores. I started dipping my toe back in with this one, starting with twice/week, and now I'm up to every other night, alternating with the GOW retinol cream. I cleanse, then apply this to my t-zone, use an oil of some sort around my eyes and cheeks, and leave for about 20 min. I then follow with a combo of a GOW serum like progeline, acai berry, ceramide, or whatever latest wonderful free sample I've received :), mixed with the bakuchiol oil, and depending on how dry I am, an ozonated oil as well. My little blocked pores are much improved! My skin texture is very soft and fine (also I think thanks to the retinol and other stuff), but this helps too. I think the biggest thing though is more noticeable fading of hyperpigmentation on my forehead! I still use the light n bright serum during the day, which did help a lot for a while, but I actually think that this has made a bigger difference recently. Love love love GOW so much, it's really impossible to express my appreciation for all you do!!!
Devotee, you are such a kind, mindful, and loyal customer. Thank you❤🙌
Thank you for such a thorough and insightful review. We are so pleased to hear that the BHA/AHA 2% Synergistic Exfo Tonic has helped refine your skin texture, minimize blocked pores, and support the fading of hyperpigmentation.
Your thoughtful approach to reintroducing acids, along with the way you have integrated this tonic into a balanced routine with retinol, serums, and nourishing oils, is precisely how we hope our products will be used.
We truly appreciate your trust in GOW and are grateful for your kind words and continued support. ⋆。‧˚ʚɞ˚‧。⋆
I've been using this for close to 10 months and I don't think I could live without it now! I think that it's best to let retinols sit for a couple hours without adding on a ton of other products so as not to neutralize them (is that right??), so I don't like serums because they make my skin feel tight, especially around my eyes, without adding a cream or oil on top. This one is so emollient and silky that I can use it alone overnight, so I feel like the retinol can really do its work. I do think that it's made a difference with fine lines and plumpness - my skin definitely does not look or feel its 40 years. I haven't taken the time to review in a while, but GOW never disappoints and I need to sing some praise for this cream!! I would honestly be lost without all of my GOW products - my bathroom drawer looks like I robbed the warehouse or something!
Hi Devotee
Thank you for sharing your experience with the Vita ReSurface Cream. We are so glad to hear it has become such an essential part of your routine and that the texture allows you to use it comfortably on its own overnight. It is wonderful to know you are seeing benefits in both skin plumpness and fine lines, and we appreciate your thoughtful approach to getting the most from your retinol.
Your kind words and continued trust in GOW mean so much to us.
Markey and the Crew @ GoW
I have never been able to use vitamin C of any kind on my face. Not sure what the difference is here but this one works great and doesn't bother me at all! I think it's helping even out my skin tone but I've only been using it maybe a month so far and in my experience you have to give things at least three months to really see results. But so far so good!
C³ Lipid Elixir
Florence
Seeing Results!
I got the 10 ml. size to sample the product and see if it does what it claims. My skin seems to like products with niacinamide in them so I thought it couldn't hurt to try TXA+Z. I'm happy to say that I'm beginning to see results regarding fading of stubborn after-blemish hyperpigmentation on my face and, while I use other products for this purpose as well, I think the TXA+Z is doing most of the heavy lifting at this point. I like the feel of this serum and have been using it in the morning. I'm back to get the 1 oz. size before I run out.
This product is amazing. My skin looks and feels better after only a couple of weeks. I am pleased. Thank you Mother Earth for the gifts Garden of Wisdom uses from you. Thank you Garden of Wisdom for using these gifts for our benefit. Blessings to all of you
Tepezcohuite Calming & Brightening Complex
Margie
Love the feel!
This feels great upon application. Really looking forward to seeing how it affects my skin.
PhytoCellTec™ Goji Berry Stem Cell Exosomes Serum
Margie
I need this!
As I’ve hit my 60s, the bags under my eyes are really getting bad. So so happy to have this incredible serum to help. I’m definitely noticing a difference.
Cellular Eye Complex - Age Defying Hydration for Delicate Skin