Micronized Trans-Resveratrol Powder is hard to find and worth the investment! One vial (1.2 grams) is enough to add to your finished product of 2 ounces (60 grams) for a 2% concentration! Estimated to be up to 300% or more, effective when mixed in a liquid or cream than any other resveratrol on the market!
Only 4mg (.0004 grams) of the powdered extract 2 times per day is equal to the resveratrol in 2 liters of wine!
Properties very effective anti-oxidant which helps to fight free radical skin damage, packed with vitamins and minerals, skin food in the form of phytonutrients (proanthocynidin), topically fights carcinogens, inhibitor of enzyme oxidative activity
INCI: Polygonum cuspidatum plant root Purity: 98% Physical Form: White Crystalline Powder Melting Point: 265-266°C Applications: Topical Usage Rate: Up to 2% (start at a .5% or lower) Solubility: Water and Alcohol Particle Size: Between 1-4 microns PH: N/A Storage: Stable/Store in a dark area void of moisture in closed container
This Resveratrol comes from the natural polygonum cuspidatum plant root. The plant root is cleaned and made into powder. The powder then goes through an extraction process using alcohol and water. The extract from the process contains concentrated phytonutrients. This polygonum powder extract is then tested specifically for Trans-Resveratrol content to assure us of the amount of Trans-Resveratrol it contains. The powder is verified a second time using HPLC scientific lab equipment at the American Analytical Chemistry Labs in Illinois, for safety and purity.
Shelf Life and Storage Information for Our Products and Ingredients
Finished Products - generally don't need to be refrigerated as they are preserved, but you can refrigerate them to extend their shelf life. The shelf life for most products is 9-12 months. Vitamin C Serum(s) and VitaResurface products should continually be refrigerated to extend their shelf life. Sample Sizes - do have a shorter shelf life (generally 3-6 months), and items in jars can dry up quicker than this if the lid is not tightened well enough (Vitamin C Serums - use within 90 days).
Please keep your products out of humidity, heat, direct light and in a dark cabinet when possible:
Exfoliating Acid - products have a shelf life of 9-12 months. The only things we don't suggest refrigerating are the Mandelic Acid Serums or Salicylic Acid Serums, as they can crystallize in the refrigerator. If this happens, you can set the product into a hot water bath to see if the crystals will dissolve.
Additional Items That Require Refrigeration and/or Kept in the Dark:
Hydrosols and Distillates - remove 1 ounce of hydrosol and add it into a separate,sterilized spray bottle and spritzer. Keep the larger bottle in the refrigerator. Carrier and Exotic Oils - generally, you can refrigerate all carrier oils, although some very rich oils will solidify. This is fine. All you have to do is take it out, warm it up at room temperature and it should liquefy. If not, set the bottle in a hot water bath and occasionally shake the bottle, which will hopefully turn into a liquid. There are some oils with a super long shelf life, like Coconut Cream and Jojoba Oil.
Refrigeration is not necessary, but it surely won't hurt:
Essential Oils - essential oils are best stored in a cool, dark place. Co2 Extracts - these should continually be refrigerated. Butters - we suggest refrigerating our "skincare" butters. You can remove what you need and keep the rest in the fridge. Clays - keep in a dry, dark place. Shelf life is at least 2 years. Herbs - all herbs (whole or ground) should be kept in a dark, cool and dry location. Herbal (liquid) Extracts - these are created using alcohol. The alcohol pulls the constituents (properties) from each herbs - root, trunk, leaves, and flowers. They have a shelf life of 3-5 years. They can be kept in the refrigerator or a dark place. Other Raw Ingredients - i.e., Sodium PCA, Honeyquat, Oat Beta Glucan, etc. will all have a different shelf life.
Resveratrol is a phenolic phytoalexin found in grape skin and other plants. It has intracellular antioxidant activity and activates SIRT1, a NAD+-dependent histone deacetylase involved in mitochondrial biogenesis and the enhancement of peroxisome proliferator-activated receptor coactivator-1a (PGC-1a) and FOXO activity. The anti-diabetic, neuroprotective and anti-adipogenic actions of resveratrol may be mediated via SIRT1 activation. That was a mouthful!!
You may have heard … that the incidence of heart disease in France is far lower than in the U.S. Scientists spent a long time trying to figure out how that could possibly be when the traditional French diet – lots of cheese, bread, sauces, wine with every meal - includes pretty much everything we’re advised not to eat. After much research, they think they’ve found the secret - an excellent anti-aging ingredient you might want to add to your skin care routine.
What is the magic ingredient? It’s called resveratrol, is found in many red wines, and is an antibiotic produced by plants when under attack by bacteria, fungi and other substances that can cause disease or illness. Although the formal research has been conducted primarily in test tubes and on animals, resveratrol has reportedly been effective in fighting viruses, inflammation, cancer and neurological diseases. It is also being touted for its anti-aging effects.
While antibiotics are not new in the skin care field for some skin diseases, it’s unusual to think that an antibiotic can also be effective when it comes to aging. However, many scientists now believe that a host of degenerative diseases are actually caused by bacteria and inflammation. That certainly is true of some skin conditions, which is one of the reasons for the popularity of antibacterial skin care products.
PubMed.gov
Delivery of resveratrol, a red wine polyphenol, from solutions and hydrogels via the skin. School of Medicine, Fu Jen Catholic University, Taipei County 242, Taiwan.
Resveratrol, the main active polyphenol in red wine, has been demonstrated to show benefits against skin disorders. The bioavailability of orally administered resveratrol is insufficient to permit high enough drug concentrations for systemic therapy. In this study, we examined the feasibility of the topical/transdermal delivery of resveratrol. The effects of vehicles on the in vitro permeation and skin deposition from saturated solutions such as aqueous buffers and soybean oil were investigated. The general trend for the delivery from solutions was: pH 6 buffer=pH 8 buffer>10% glycerol formal in pH 6 buffer>pH 9.9 buffer>pH 10.8 buffer>soybean oil. A linear relationship was established between the permeability coefficient (K(p)) and drug accumulation in the skin reservoir. Viable epidermis/dermis served as the predominant barrier for non-ionic resveratrol permeation. On the other hand, both the stratum corneum (SC) and viable skin acted as barriers to anionic resveratrol. Several prototype hydrogel systems were also studied as resveratrol vehicles. The viscosity but not the polarity of the hydrogels controlled resveratrol permeation/deposition. Piceatannol, a derivative of resveratrol with high pharmacological activity, showed 11.6-fold lower skin permeation compared to resveratrol. The safety profiles of resveratrol suggested that the hydrogel caused no SC disruption or skin erythema. It was concluded that delivery via a skin route may be a potent way to achieve the therapeutic effects of resveratrol. This is the first report to establish the permeation profiles for topically applied resveratrol.
