In "in vitro" human skin cultures, topical application of N-acetyl glucosamine and niacinamide stimulated hyaluronan synthesis. These treatments also led to an increase in collagen (procollagen-1) expression. Twice daily use of a facial moisturizer containing a combination of N-acetyl glucosamine and niacinamide for 4 to 8 weeks by women with moderate to severe fine and wrinkles reduced the appearance of facial fine lines and wrinkles, particularly in the eye area of the face. The in vitro hyaluronan results suggest that this effacement of fine lines and wrinkles is due at least in part to improved hydration of the skin. There are specific percentages in the actives used although this is considered proprietary information.
References 1.Sayo T, Sakai S, Inoue S. Synergistic effect of N-acetylglucosamine and retinoids on hyaluronan production in human keratinocytes. Skin Pharmacol Physiol 2004; 17: 77-83. 2.Ghersetich I, Lotti T, Campanile G et al. Hyaluronic acid in cutaneous aging. Int J Dermatol 1994; 33: 119-22. 3.Weindl G, Schaller M, Schafer-Korting M, Korting HC. Hyaluronic acid in the treatment and prevention of skin diseases: molecular, biological, pharmaceutical and clinical aspects. Skin Pharmacol Physiol 2004; 17: 207-13.
Method of Application
Apply a pea-sized amount of this serum to your face and neck. Spritzing your face with spring water or a hydrosol will help this serum to glide across the skin gently yet effectively.
Shelf Life and Storage Information for Products and Ingredients
Finished products generally don't need to be refrigerated as they are preserved, but you can refrigerate them to extend shelf life. Shelf life is 9 - 12 months
Sample sizes do have a shorter shelf life (generally 3-6 months and items in jars can dry up quicker than this if the lid is not tightened well enough (except our vitamin C serums - use within 90 days).
Please try to keep out of high humidity or heat if possible! Store out of direct light and in dark cabinet if possible also!
Exfoliating Acid products will last 1 year.
The only thing we don't suggest refrigerating is the mandelic or salicylic acid serums as those can crystallize in the refrigerator and not go back to their normal state even if you warm them up.
Additional Items Requiring Refrigeration
Hydrosols - Take out 1/2 oz to 1 oz in a separate spray bottle from your original container and keep the larger bottle in the refrigerator!
Carrier Oils - Generally you can refrigerate ALL carrier oils, they will solidify in some cases. This is FINE all you have to do is take it out warm it up at room temp and it will be liquid again!
There are some oils that have a super long shelf life like coconut oil for instance! That does not need to be refrigerated, but it cannot hurt it either!
Essential Oils - Essential oils are best stored in a cool dark place.
Co2 Oils - These should always be refrigerated.
Butters - We suggest refrigerating our skincare butters. You can take out what you need and keep the rest in the fridge.
Essential oils - These can be refrigerated to increase their shelf life!
Clays - Keep in a dry, dark place (shelf life is at least 2 years)
Herbs - (whole or ground) These should last a good year at least - Keep in a dark, cool and dry location.
Herbal Extracts - [powder] Keep these also in a dark, DRY place. You can keep in the fridge, but make sure the seal is on very tight so you don't get moisture in. [1 year at least].
Herbal Extracts - [liquid] These can be kept in the refrigerator (or a dark DRY place] [3 years at least]
Other Various Raw Ingredients - i.e. Sodium PCA, Honeyquat, Iat Beta Glucan etc will all have a different shelf life (we are working on adding this to the ingredient pages.
Niacinimide skin lightening, anti-aging agents, stimulates circulation, anti-inflammatory
N-Acetyl Glucosamine glucose based monosaccharide, anti-inflammatory, antioxidant, naturally increases natural production of hyaluronic acid, promising evidence showing this helps to fight hyperpigmentation
Cosmocil CQ (Polyaminopropyl Biguanide) preservative that does not contains parabens or formaldehyde releasers
Locust Bean Gum natural thickener
Please reach out with any questions! Call or email us and we will get back to you as soon as possible.
Mon - Fri: 10:00-3:00 MST