Our original Progeline™ formula combines targeted peptides with Hydrolyzed Elastin to support firmer, smoother-looking skin.
Antioxidants, beta-glucan, and Wild Yam Root Extract help condition tired, less resilient skin.
Why You’ll Love It
This lightweight serum brings together two targeted peptides, antioxidant support, and comforting skin-conditioning ingredients. It layers easily into a daily routine while helping mature skin look smoother, firmer, and more resilient.
Key Benefits
➤ Supports a firmer, smoother-looking complexion
➤ Helps soften the appearance of fine lines
➤ Provides antioxidant support against environmental stress
➤ Conditions skin with Hydrolyzed Elastin Protein and beta-glucan
➤ Feels lightweight and layers easily into a daily routine
Featured Ingredients
Trifluoroacetyl Tripeptide-2 Supports the appearance of firmness, elasticity, and smoother-looking skin.
Palmitoyl Tripeptide-5 Supports visibly plumper, firmer, and more refined-looking skin.
Hydrolyzed Elastin Protein A skin-conditioning protein that helps skin feel soft, smooth, and more supple.
Wild Yam Root Extract A botanical extract selected for its conditioning qualities.
Oat Beta-Glucans Helps comfort, condition, and support the skin.
Resveratrol and Superoxide Dismutase Provide antioxidant support against environmental stress.
How to Use
1. Apply a few drops to clean skin.
2. Gently pat over the face, neck, and décolleté.
3. Follow with a hydrator, moisturizer, or facial oil.
4. Use morning and/or evening.
Best For
➤ Skin showing visible signs of aging
➤ Skin that feels thin, tired, or less resilient
➤ Those wanting targeted peptide support
➤ Those who prefer the conditioning qualities of the Hydrolyzed Elastin formula
Shelf Life and Storage Information for Our Products and Ingredients
Finished Products - generally don't need to be refrigerated as they are preserved, but you can refrigerate them to extend their shelf life. The shelf life for most products is 9-12 months. Vitamin C Serum(s) and VitaResurface products should continually be refrigerated to extend their shelf life. Sample Sizes - do have a shorter shelf life (generally 3-6 months), and items in jars can dry up quicker than this if the lid is not tightened well enough (Vitamin C Serums - use within 90 days).
Please Keep Your Products Out of Humidity, Heat, Direct Light and in a Dark Cabinet When Possible
Exfoliating Acid - products have a shelf life of 9-12 months. The only things we don't suggest refrigerating are the Mandelic Acid Serums or Salicylic Acid Serums, as they can crystallize in the refrigerator. If this happens, you can set the product into a hot water bath to see if the crystals will dissolve.
Additional Items That Require Refrigeration and/or Kept in the Dark
Hydrosols and Distillates - remove 1 ounce of hydrosol and add it to a separate, sterilized spray bottle and spritzer. Keep the larger bottle in the refrigerator. Carrier and Exotic Oils - generally refrigerate all carrier oils, although some very rich oils will solidify. This is fine. All you have to do is take the oil out, warm it up at room temperature, and it should liquefy. If not, set the bottle in a hot water bath and occasionally shake the bottle, which will hopefully turn into a liquid. Some oils, like coconut cream and jojoba oil, have a super long shelf life.
Refrigeration of The Following Ingredients is Not Necessary, But it Won't hurt
Essential Oils - essential oils are best stored in a cool, dark place. Co2 Extracts - these should continually be refrigerated. Butters - we suggest refrigerating our "skincare" butters. You can remove what you need and keep the rest in the fridge. Clays - keep in a dry, dark place. Shelf life is at least 2 years. Herbs All herbs <i>(whole or ground)</i> should be kept in a dark, cool, and dry location. Herbal (liquid) Extracts are created using grain alcohol. The alcohol pulls the constituents (properties) from each herb, root, trunk, leaf, and flower. They have a shelf life of 3-5 years. They can be stored in the refrigerator or a dark, dry place. Other Raw Ingredients - such as Sodium PCA, Honeyquat, Oat Beta Glucan, etc., will all have different shelf lives.
Shipping Transit Note: Some customers have asked whether products can be affected by time in transit, especially during warmer months. Our products are formulated and preserved to remain stable during normal shipping times and should not spoil simply from being in transit.
That said, if you are concerned about heat exposure, you are welcome to add an ice pack to your order for extra peace of mind. Click here to add an ice pack.
Ingredient Transparency
Each ingredient is shown with its INCI, the standardized name used on cosmetic ingredient labels.
Glacial Water | INCI: Aqua (Water)
Creates the fresh, lightweight base of the serum and helps deliver its water-soluble ingredients evenly across the skin.
Wild Yam Root Extract | INCI: Dioscorea Villosa (Wild Yam) Root Extract
A botanical extract selected for its skin-conditioning qualities and ability to support a softer, more comfortable feel.
Hydrolyzed Elastin Protein | INCI: Hydrolyzed Elastin
A skin-conditioning protein that helps the skin feel soft, smooth, supple, and comfortably conditioned.
Oat Beta Glucans | INCI: Beta-Glucan
Helps comfort and condition the skin while supporting a smoother, less stressed appearance.
Progeline™ | INCI: Glycerin, Aqua (Water), Dextran, Trifluoroacetyl Tripeptide-2
A targeted peptide blend chosen to support the appearance of firmer, smoother, and more resilient-looking skin.
Syn®-Coll | INCI: Glycerin, Aqua (Water), Palmitoyl Tripeptide-5
A peptide blend that supports visibly plumper, firmer, and more refined-looking skin.
Leucidal® SF | INCI: Lactobacillus Ferment
A fermentation-derived ingredient used as part of the formula’s preservation system.
Resveratrol | INCI: Resveratrol
An antioxidant that helps support the skin against visible effects associated with environmental stress.
Superoxide Dismutase | INCI: Superoxide Dismutase
An antioxidant enzyme included to help support a healthier, more resilient-looking complexion.
What Does INCI Mean?
INCI stands for International Nomenclature of Cosmetic Ingredients.
These are the standardized names used to identify cosmetic ingredients.
To learn what each ingredient is and why it is included, choose the Ingredient Transparency tab directly to the left.
So far my skin likes this after spritzing with hydrosol. Then I mix a little with sweet almond oil to help seal it in. It doesn't clog my pores or make me break out like other products. Thank you!
Hi Karen, thank you for sharing your experience.
We're so grateful you shared your experience that the Progeline™ Peptide Repair Serum works well with your skincare routine.
Your feedback is greatly appreciated!
Wishing you the very best in your skincare journey,
Markey & Your GoW Crew ִֶָ ࣪ ִֶָ་༘࿐
a
anne marie waldron
no change
no change whatsoever
Anne Marie 🌞
We are genuinely sorry you didn't see the changes you were hoping for. Skincare results can vary widely from person to person, but we never want anyone to feel disappointed after choosing one of our products. We'll reach out privately to learn more about your experience and see how we can help.
Markey
Owner/Founder
Garden of Wisdom
T
TONI B.
Awesome progeline peptide repair serum
I have this product daily for over a year and my skin has never looked to smooth. It has helped my fine lines so much that they are barely visible
A full year of daily use gives you a wonderful perspective on how a formula truly performs, Toni. (❀❛ ֊ ❛„)♡
Peptide serums are all about consistency, so we love hearing how much smoother your skin looks and how dramatically the appearance of your fine lines has softened. Thank you for staying with our Progeline™ Peptide Repair Serum and sharing your results!
This is exciting news!
Markey ❤️❤️❤️
L
Lyn
VISIBLE EFFECTS IN AGING SKIN
This product has made the most difference to fine lines and wrinkles of any one product I use, especially in DEEP FROWN LINES IN LOWER FACE - and I use a lot of serums! It is definitely worth the price - the most I've ever spent on any skincare product. After trying the small-sized bottle, I purchased the 4 oz bottle at regular price and bought another bottle two weeks later during GOW's spring sale!
Lyn ... Thank you!
This means so much… truly ❤️
Hearing that it’s making a visible difference, especially in deeper lines, is something we never take lightly. And the fact that you came back for the larger size, and then again during the sale… that kind of trust means everything to us.
Thank you for sharing this so thoughtfully.
Markey, Jen, and our amazing team ͙֒
K
Kimberly Dognaux
ProgelinePeptide Repair Serum
So far, good!! The serum goes on smoothly and soaks into my skin. This will be a nice addition to my skin care routine.
Kimberly
Thank you for the kind review. This has been a popular product for so many years; it's crazy.
You defined it perfectly; as it goes on smoothly and soaks right in. Well done!
Your Gow Team
This is delightful. I think it was on sale or I got a.sample to try and loved it. One thing to note: it smells lovely but does not smell like mango. I misunderstood that the first time I ised it. It light, rich, absorbs easily, and leaves no weird texture afterwards. A very lovely experience.
Flirty Mango Body Cream
Anonymous
Just coming to the page to repurchase
Just coming to the page to repurchase. This product is great for my sensitive skin--keeps it clear without burning.
LactiSen Gel 2%
Cynthia Wells
I love this product
I love this product.Leaves your skin clean and it doesn’t feel stripped.
Skin Friendly Cucumber Cleanser
Mar
Love the scent and makes skin soft and smooth
Love the scent and makes skin soft and smooth when used with amla oil on face.
Hyssop Blossom Hydrosol
Ladylailey
My face loves this facial balm !!
Love this new formula with the frankincense so much that I had to get the larger size! I've been using hyaluronic acid plus squalane oil as a moisturizer because I couldn't find a moisturizer that didn't irritate my face or make it drier. I like that this balm has a few simple amazing ingredients with no added fragrance or preservatives. It doesn't irritate my skin or flare up my rosacea. This is the only moisturizer that has actually provided hydration for my skin. I use a small dab at night so the product lasts for many months and leaves my skin with a healthy glow.
This is still my favourite cleanser after many many bottles! It never fails. So gentle it Doesn’t leave my skin dry yet still is cleansing and refreshing - my go to!
Soothing Cleansing Gel 100% Soap Free
Anonymous
Awesome
I really love this product, I am 44 and it has helped the area around my eyes and around my mouth. My skin appears firmer. Only problem is it is always sold out when I go to order more!
Neurophroline® Skin Stress Serum
Anonymous
Honestly so impressed with this gel
Honestly so impressed with this gel. Very hydrating and non irritating for sensitive skin.
Encapsulated Glacier Water Hydrating Gel
Christine Rabena
A product that really works!
In my 70yrs still having breakouts, trying EVERYTHING!!! Prescription and over the counter. This is the 1st product I’ve ever used, that really works!! Will definitely reorder and recommend!
Thanakha Blemish Clearing Tonic
Sarah Dawson
Such a lovely oil!
Such a lovely oil!
It glides on so smoothly, feels like a substantial oil without leaving me greasy, and I love that it has a mild color so I can put it on directly. I live in the Southwest so it’s so fun to use the oil from a plant that I see around me all the time! Thank you Garden of Wisdom for being the oasis in the desert and delivering such wonderful products!
Prickly Pear Seed Oil - The Secret to Timeless Radiance
This is delightful. I think it was on sale or I got a.sample to try and loved it. One thing to note: it smells lovely but does not smell like mango. I misunderstood that the first time I ised it. It light, rich, absorbs easily, and leaves no weird texture afterwards. A very lovely experience.
🌼🌼🌼 Thank you for your lovely review! We're glad you enjoyed the cream and its texture. We'll keep in mind your note about the scent. Hope you continue to love it!
The Mango you are referencing is the Mango Butter as we don't use fragranced oils in our products. We can add some scents just contact us privately as we have essential oils and blends that you may enjoy.
Thank you, again,
Your GoW Team ᵗʰᵃᶰᵏᵧₒᵤ! ✌︎㋡
Just coming to the page to repurchase. This product is great for my sensitive skin--keeps it clear without burning.
Hi there! We're so glad to hear that LactiSen Gel 2% works well for your sensitive skin.
Thanks for your continued trust in Garden of Wisdom Skincare and our Team! 😊
Love the scent and makes skin soft and smooth when used with amla oil on face.
Hi Maria ᵗʰᵃᶰᵏᵧₒᵤ! ✌︎㋡
We're happy to hear you love the scent and how it leaves your skin feeling soft and smooth.
Thanks for sharing your experience!
Your GoW Team 😊
Love this new formula with the frankincense so much that I had to get the larger size! I've been using hyaluronic acid plus squalane oil as a moisturizer because I couldn't find a moisturizer that didn't irritate my face or make it drier. I like that this balm has a few simple amazing ingredients with no added fragrance or preservatives. It doesn't irritate my skin or flare up my rosacea. This is the only moisturizer that has actually provided hydration for my skin. I use a small dab at night so the product lasts for many months and leaves my skin with a healthy glow.
Hi Teresa, your review truly makes us smile. I always read reviews out loud and I know the staff here is very proud of their work. Knowing this facial balm works so well for your skin is awesome to hear! Thank you for sharing your experience and for being a loyal customer.
Wishing you continued glowing skin!
Your GoW Team ˖˳·˖ ִֶָ ⋆🪷⋆ ִֶָ˖·˳˖ ִֶָ