There are three processes in face aging: cellular aging, cutaneous aging, and structural aging, which is where Adipofill™ fits in. Structural aging decreases adipose tissue, which is responsible for facial plumpness. As we age, this "fat pad progressively melts due to a disturbance of adipocyte metabolism, which causes the appearance of deep nasolabial folds, saggy jowls and hollowness under the eyes."
Adipofill™ was engineered to mimic lipofilling results (such as those used in plastic surgery) by activating hypoxia-inducible factor (HIF)-1-alpha, a transcription factor. This stimulates adipocyte anabolism and decreases fatty acid release, ultimately reducing nasogenian wrinkles for a plumper and youthful look and offering facial rejuvenation.
Adipofill™ reproduces the lipo hormesis phenomenon by activating HIF-1α gene expression and related genes involved in the global adipocyte anabolism.
Adipofill™ therefore, mimics lipofilling results in a non-surgical way. By acting on adipose tissue growth with a bio-controlled and non-invasive mechanism.
Adipofill™ clinically reverses the age-related signs Adipofill™ is thus an innovative, sophisticated, high-tech ingredient that fights the aging process for a plump and youthful look.
NOTE: A couple of our customers developed a rash with this serum, followed by tiny bumps. Double-check to make sure the ingredients are adaptable to your skin profile.
Shelf Life and Storage Information for Our Products and Ingredients
Finished Products - generally don't need to be refrigerated as they are preserved, but you can refrigerate them to extend their shelf life. The shelf life for most products is 9-12 months. Vitamin C Serum(s) and VitaResurface products should continually be refrigerated to extend their shelf life. Sample Sizes - do have a shorter shelf life (generally 3-6 months), and items in jars can dry up quicker than this if the lid is not tightened well enough (Vitamin C Serums - use within 90 days).
Please keep your products out of humidity, heat, direct light and in a dark cabinet when possible:
Exfoliating Acid - products have a shelf life of 9-12 months. The only things we don't suggest refrigerating are the Mandelic Acid Serums or Salicylic Acid Serums, as they can crystallize in the refrigerator. If this happens, you can set the product into a hot water bath to see if the crystals will dissolve.
Additional Items That Require Refrigeration and/or Kept in the Dark:
Hydrosols and Distillates - remove 1 ounce of hydrosol and add it into a separate,sterilized spray bottle and spritzer. Keep the larger bottle in the refrigerator. Carrier and Exotic Oils - generally, you can refrigerate all carrier oils, although some very rich oils will solidify. This is fine. All you have to do is take it out, warm it up at room temperature and it should liquefy. If not, set the bottle in a hot water bath and occasionally shake the bottle, which will hopefully turn into a liquid. There are some oils with a super long shelf life, like Coconut Cream and Jojoba Oil.
Refrigeration is not necessary, but it surely won't hurt:
Essential Oils - essential oils are best stored in a cool, dark place. Co2 Extracts - these should continually be refrigerated. Butters - we suggest refrigerating our "skincare" butters. You can remove what you need and keep the rest in the fridge. Clays - keep in a dry, dark place. Shelf life is at least 2 years. Herbs - all herbs (whole or ground) should be kept in a dark, cool and dry location. Herbal (liquid) Extracts - these are created using alcohol. The alcohol pulls the constituents (properties) from each herbs - root, trunk, leaves, and flowers. They have a shelf life of 3-5 years. They can be kept in the refrigerator or a dark place. Other Raw Ingredients - i.e., Sodium PCA, Honeyquat, Oat Beta Glucan, etc. will all have a different shelf life.
Spring Water - hydrating, natural solvent Anemarrhena Asphodeloides Root Extract - skin plumping Panthenol B-5 - penetrating moisturizer, soothing, healing, encourages cell regeneration Glycoproteins - aids in the cellular repair process, boosts the skin's oxygen content, increases the energy level of skin cells by enhancing the production of energy-rich adenosine triphosphate, high in polysaccharides which allows for extra hydration to the skin. Glycoproteins boost the skin's oxygen content, increase the cellular respiration capacity, and increase the energy level of skin cells by enhancing the production of energy-rich adenosine triphosphate (ATP). Glycoproteins also have moisturizing properties due to their content of water-binding polysaccharides. Adipofill™ - (we formulate with the strongest percentage recommended by the manufacturer) a patented L-ornithine amino acid encapsulated in an Ionosome. is thus an innovative, sophisticated, and high-tech ingredient that fights the aging process for a plump and youthful look. Aspen Bark Extract - preservative, gentle exfoliator, anti-bacterial Astaxanthin - naturally-occurring carotenoid found in algae, anti-oxidant, anti-inflammatory Resveratrol - functions (in plants) as a phytoalexin, a substance produced by plants that can inhibit the growth of infecting fungi or other pathogens. Resveratrol presents itself with antiviral, antioxidant, anti-inflammatory, and neuroprotective activities which fights the degradation of cell functioning to fight the free-radicals Xanthan Gum - natural thickener
I have had great luck with Adipofil! It has definitely added volume to my face. I use this serum every evening. As we age, we noticeably lose volume in our face and I will use anything that might help to maintain it!
Thank you for the review, Valerie.
We know it takes time from your busy day to list reviews and yours are
dearly appreciated.
Your GOW team :-D
M
Mary Gleason
Love item
Only using for a short time so far but feel Im already noticing positive results and seem to notice less hollowing in areas of concern. Very pleased! Am gonna keep using. Great product!
Mary,
Thank you for this review! This is one product that will work given time depending on how long the customers have had to deal with the 'hollowing'.
It's always important that customers are able to read others results.
Again, thank you!
Markey
A
Anne
A great addition
I enjoyed using this product. It plumped out fine lines and added in other problem areas. I love trying things I don’t see in other skin care lines. Thanks gow for something new.
