Sometimes your skin is not dry, not oily, not even reactive... it is simply overwhelmed. It stops responding the way it used to. It looks a little more tired, a little less even, a little harder to settle. This is where Revitalize Your Skin Serum with Neurophroline™ begins.
This silky, lightweight serum was created for skin that is carrying the effects of daily stress. Not to force change, but to gently support a calmer, more balanced appearance. Skin is left looking more even, more rested, and more at ease.
At the center of this formula is Neurophroline™, a wild indigo seed extract chosen specifically for its ability to help reduce the visible effects of stress on the skin by reducing cortisol production locally in the skin cell. Rather than pushing the skin harder, it works in a quieter way, supporting a more refreshed, balanced complexion over time.
We paired it with Oat Beta Glucan, Thermo-stressine, Superoxide Dismutase, and other carefully chosen ingredients that help comfort the skin and defend against visible environmental strain.
This is not about pushing the skin harder. It is about helping it find its way back to balance.
Key Benefits
➜ Helps reduce the visible effects of daily skin stress
➜ Supports a calmer, more balanced-looking complexion
➜ Helps improve the appearance of uneven tone and fatigue
➜ Lightweight hydration without heaviness or buildup
➜ Supports skin exposed to environmental and emotional stress
Why It Feels Different
When skin is under ongoing stress, it does not always react loudly. Instead, it can begin to look duller, feel less comfortable, or lose some of its natural balance. This formula was designed with that in mind.
Neurophroline™ helps target the visible effects of stress on the skin, while Oat Beta Glucan helps soothe and support the skin barrier. Thermo-stressine helps support skin exposed to changing environmental conditions, and Superoxide Dismutase offers antioxidant support to help defend against visible oxidative stress.
Together, these ingredients create a serum that feels light, calm, and supportive, especially for skin that needs less pressure and more consistency.
Method of Application
Apply a small amount to clean skin after your water-based layers and before heavier serums, oils, or creams. Gently smooth over the face, focusing on areas that appear tired, uneven, or stress-worn. Use morning, evening, or both.
Featured Ingredients
➜Neurophroline™ – is a wild indigo seed extract that helps stressed skin calm down. Skin cells can produce cortisol locally in response to stress, and when cortisol stays elevated it can show up as redness, dullness, dehydration, and a more reactive barrier. Neurophroline is designed to help reduce cortisol production in skin cells while also encouraging the release of a calming neuropeptide (beta-endorphin), which supports a more balanced, refreshed-looking complexion over time.
➜Oat Beta Glucan – Helps soothe and support the skin barrier, contributing to a calmer feel.
➜Thermo-stressine – Helps support skin exposed to environmental stress and fluctuating conditions.
➜Superoxide Dismutase (S.O.D.) – An antioxidant enzyme that helps defend against visible oxidative stress.
Technical Notes
Neurophroline™ is derived from Wild Indigo (Tephrosia purpurea). This specialized extract contains naturally occurring sugars, including stachyose and ciceritol, and has been studied for its ability to help visibly improve skin tone and reduce the appearance of stress-related skin fatigue.
Shelf Life and Storage Information for Our Products and Ingredients
Finished Products - generally don't need to be refrigerated as they are preserved, but you can refrigerate them to extend their shelf life. The shelf life for most products is 9-12 months. Vitamin C Serum(s) and VitaResurface products should continually be refrigerated to extend their shelf life. Sample Sizes - do have a shorter shelf life (generally 3-6 months), and items in jars can dry up quicker than this if the lid is not tightened well enough (Vitamin C Serums - use within 90 days).
Please Keep Your Products Out of Humidity, Heat, Direct Light and in a Dark Cabinet When Possible
Exfoliating Acid - products have a shelf life of 9-12 months. The only things we don't suggest refrigerating are the Mandelic Acid Serums or Salicylic Acid Serums, as they can crystallize in the refrigerator. If this happens, you can set the product into a hot water bath to see if the crystals will dissolve.
Additional Items That Require Refrigeration and/or Kept in the Dark
Hydrosols and Distillates - remove 1 ounce of hydrosol and add it to a separate, sterilized spray bottle and spritzer. Keep the larger bottle in the refrigerator. Carrier and Exotic Oils - generally refrigerate all carrier oils, although some very rich oils will solidify. This is fine. All you have to do is take the oil out, warm it up at room temperature, and it should liquefy. If not, set the bottle in a hot water bath and occasionally shake the bottle, which will hopefully turn into a liquid. Some oils, like coconut cream and jojoba oil, have a super long shelf life.
Refrigeration of The Following Ingredients is Not Necessary, But it Won't hurt
Essential Oils - essential oils are best stored in a cool, dark place. Co2 Extracts - these should continually be refrigerated. Butters - we suggest refrigerating our "skincare" butters. You can remove what you need and keep the rest in the fridge. Clays - keep in a dry, dark place. Shelf life is at least 2 years. Herbs All herbs <i>(whole or ground)</i> should be kept in a dark, cool, and dry location. Herbal (liquid) Extracts are created using grain alcohol. The alcohol pulls the constituents (properties) from each herb, root, trunk, leaf, and flower. They have a shelf life of 3-5 years. They can be stored in the refrigerator or a dark, dry place. Other Raw Ingredients - such as Sodium PCA, Honeyquat, Oat Beta Glucan, etc., will all have different shelf lives.
Spring Water hydrating and helps prepare the skin to accept active ingredients Liposomes (phospholipids) penetration enhancer and extremely hydrating Leucidal SF (Lactobacillis Ferment) gentle preservative without parabens or formaldehyde releasers Neurophroline this exclusive extract has demonstrated its unique biological capabilities to break down the cortisol production by skin cells, activate the release of a natural calming neuropeptide acting to reduce redness, and enhance the overall appearance of the skin. Thermostressine® (tetrapeptide)this tetrapeptide increases the skin's tolerance to jet-lag and other daily lifestyle stresses. The proteotoxic stress is well controlled and damage prevented. Oat Beta Glucans are being studied for their potential immunomodulatory effects, anti-tumor properties, and stimulation of collagen deposition. Oat Beta Glucans have amazing healing properties.
Hyaluronic Acid (high molecular weight)Hyaluronic acid is a natural polysaccharide (large sugar molecule) that occurs in various tissues (skin, synovial fluids of joints, connective tissues).
Hyaluronic Acid(super low molecular weight)hyaluronic acid (sodium hyaluronate) is a natural polysaccharide (sugar) that occurs in body tissues including the skin providing hydration, stability, lubrication. This super low-molecular-weight form is made by enzymatically cleaving high-molecular weight hyaluronic acid into small fragments.
Dehydroxanthan Gumis obtained from fermented polysaccharides.This ia natural thickener. AllTrans ResveratrolAllTrans-resveratrol is a naturally occurring compound in certain plants, particularly grapes and red wine. It has been of interest in skincare and cosmetics due to its potential antioxidant and anti-aging properties. When applied topically to the skin, trans-resveratrol can exhibit several beneficial properties like antioxidant protection, anti-inflammatory, skin brightening, UV protection, collagen production and really keeps the skin hydrated. Apple Polyphenols are natural compounds found in apples, particularly in the skin and seeds of the fruit. They are a type of phytochemical, which means they are plant derived. Apple polyphenols, when used in topical applications, offer antioxidants, UV Protection, anti-inflammatory effects, they improve skin hydration while boosting collagen production. Yes, they are this good. Sclerotium Gum is a naturally derived, gel-like polysaccharide (sugar-based) thickener. Super Oxide Dismutase (S.O.D.) the highly purified superoxide dismutase made from Saccharomyces cerevisiae for skin care products. Offering anti-aging and skin-whitening properties while providing potent antioxidant effects inhibiting free radical formation.
This serum is a lovely tool in fighting signs of aging cause by lifes little stressors :)
Thank you, Erika.
You are adorable. We are always happy to hear when a product shows the results
one is hoping for.
Thank you for the video!
Markey ˚⊱⊰˚
A
Anonymous
Love it!
I love this product & so does my skin! For me, that is a huge blessing.
Hi Elayne!
Thank you for mentioning this product. It doesn't get enough ❤️.
Wishing you the best, as always, with your skincare journey.
Markey and Your GoW Crew of Lovlies.
˖˳·˖ ִֶָ ⋆͙⋆ ִֶָ˖·˳˖ ִֶָ
R
Rachel
Staple!!
Love love all GoW products I've tried, but this one was particularly interesting because of the Cortisol component! My skin has been a challenge the last 10 years and a lot of that was likely due to stress and hormones. In the last few years, things seemed to have leveled out but I still need support of course. I really do believe in a week or so I saw results from this serum. My skin is happy and hydrated! About to reorder my 2nd bottle :)
This is such a thoughtful review, and we're SOO happy for your results! Thank you so much :)
F
Frances S
Amazing product
I used this serum for the first time this week and I swear my skin immediately felt immediate relief. My skin actually feels satiated when I apply the serum. It is more even and glowing. I’m obsessed and hope this product is restocked asap. Thank you garden of wisdom!!!
Frances! I couldn't agree more! We tested this for awhile before releasing it and this product really is a game changer especially for those of us who find it more challenging to keep our skin hydrated and beautiful.
Thank you for the wonderful review, we always appreciate reviews.
Markey :-D
I love this schampoo!! I was a little skeptical if an all natural shampoo would work, especially since I have fine, straight hair that tends to get greasy after only a couple of days with regular high quality shampoos, but this really works. I can go for 3 full days without washing it and I immediately noticed how powder soft my hair felt after the first wash. I think it even washes out the hard water. I will definitely be buying this again!
Locks of Lovely Shampoo (Unscented): Pure, Nourishing, and Gentle Care for Your Hair
Anonymous
Interesting new product
Interesting new product. I prefer the beautiful eye serum but this has some great ingredients
Blue Lotus Veil Peptide Infusion: Eye & Facial Renewal Serum
Teal Schinkel
ONLY MOISTURIZER THAT DOESNT CAUSE ACNE
Literally the only one I've ever used and I've searched for 30 yrs. Just the best!
Decadent Oat Enriched Emulsion
Teal Schinkel
Works on Melasma!
Nothing has worked so far on my Melasma as well as this. My skin has a glow that it doesn't have when I'm not using. And it's keeping acne at bay. There's a noticeable difference when I don't use this. Don't want to go without.
Clear, Brighten, and Prevent Serum
Rebekah Eustis
great for removing thick sunscreen
This micellar water is the best! I am in the ocean a lot and so wear thick mineral waterproof sunscreen. In the past, trying to get it all off so that my skin didn't break out was always a challenge because the foaming cleansers would dry out my skin. That is why this is a life saver. As another review mentioned, I shake the bottle, pour about a teaspoon or so in my palm and smooth over my face and neck. You can literally see the sunscreen (or make up) melt off. I rinse and then cleanse one more time with the gentle cleansing gel (another winner IMO). My skin is clean but not dry! I love the sensitive formula. Thank you GOW for making such amazing products!
Micellar Cleansing Dew | Sensitive Profile
CT
If I could only use one skincare brand for the rest of my life.
It would truly be garden of wisdom. I started using GOW about 8 or 9 years ago and have never looked back. I haven’t been disappointed by a single product, and I have tried soo many and would bathe in them all daily if I could. several have become staples in my routine, which is about 75% gow products now. The education they provide is genuinely game changing. You not only understand what you’re using and why, but the results are noticeably better than any other store brand skincare I’ve tried.
The company itself is lovely. It’s built on education, research, and experience, not marketing, trends, fake reviews, or the deceptive tactics most skincare brands rely on. Their success comes from a real commitment to honestly informing and educating their community while making truly amazing skincare. Thank you🤍
Garden Of Wisdom Skincare
Margie
Shrinks those bags!
I use this when I’m going out for something special I want to look my best. It really does shrink those puffy tissues around the eyes. It’s a great quick fix item.
Anti-Puffy Eye Serum
Margie
Lovely, soft skin!
Do you know the expression, “If I could bathe in this stuff, I would.”? Well, I do! I know this is an expensive option, but I use this as my body wash for my dry and sensitive body skin. Luckily, a little goes a long way. It’s so gentle and leaves my skin nice and clean, but also super soft at the same time. I use the Honey Butter cleanser on my face and this duo works really well for me.
Oats Milk and Honey Facial Cleanser
Anonymous
C3 Lipid Elixer
I tried this on a whim & I am so happy that I did! My skin is a bit sensitive, as well as very moody. This elixir works with my skin. My skin actually looks better.
Thank you!
C³ Lipid Elixir
Harmony Jensen
Perfect level of moisture.
I use this at night with a few drops of an oil and it’s the perfect level of moisture for my skin, even during winter. Heavy creams cause issue for me and this is perfect.
Decadent Oat Enriched Emulsion (No Essential Oils)
I love this schampoo!! I was a little skeptical if an all natural shampoo would work, especially since I have fine, straight hair that tends to get greasy after only a couple of days with regular high quality shampoos, but this really works. I can go for 3 full days without washing it and I immediately noticed how powder soft my hair felt after the first wash. I think it even washes out the hard water. I will definitely be buying this again!
Interesting new product. I prefer the beautiful eye serum but this has some great ingredients
Thank you so much for this review. We really appreciate you giving Blue Lotus Veil a try and sharing your thoughts with us.
The Beautiful Eye Serum will always have a special place in our hearts too 😊 but we’re so happy you noticed the thoughtful ingredient profile in Blue Lotus Veil. We wanted it to feel like a beautiful extension of that same peptide-loving philosophy while offering a slightly different experience for the skin.
Thank you again for your honesty, support, and for spending time exploring our creations with us.
It truly means a lot to our small team
I love this serum so much I had to write another review! This is my number one anti-aging go to every night because it’s packed with all of the top anti-aging ingredients! It’s the first thing I put on my face after washing. It has completely changed the texture of my skin! I have large pores so I am not fortunate enough to have skin like porcelain, but the clarity and softening of lines and wrinkles has been amazing! The scent…not heavy or perfumey, but simply real rose petals in a bottle, LOVE!!!
Kerrie Thank you so incredibly much for not only this beautiful review, but for coming back to write another one.
That is so cool and greatly appreciated.
We always love seeing you in the shop, and hearing how much Rose Stem Cell & Peptide Serum has become part of your nightly ritual just makes our hearts happy. Your description of the scent being like “real rose petals in a bottle” honestly could not have been more perfect.
And, thank you for sharing your experience so openly. So many people feel self-conscious about texture and pores, so hearing that you’ve noticed clarity, smoother texture, and softened lines will be incredibly encouraging for others too. We formulated this serum to feel nurturing, active, and beautifully supportive to the skin, so hearing feedback like this reminds us why we do what we do.
We adore you and appreciate your kindness and support!
Your Team @ GoW
I really like this stuff! I have super sensitive, fungal acne-prone skin. This takes off makeup and sunscreen right away, and it doesn't feel stripping or irritating. If I use it on the skin near my eyes it stings just a bit, hence the 4 stars, but it's not to stop using it. In the morning I use it as my sole cleanser, and at night I follow it with a GoW cleanser in the shower.
Thank you so much, Caroline. We really appreciate you taking the time to leave such a thoughtful and detailed review.
Hearing that Micellar Cleansing Dew has worked well for your super sensitive, fungal acne-prone skin means a lot to us, especially since skin like yours can be incredibly difficult to please without irritation. We’re so happy it’s helping remove makeup and sunscreen gently without leaving your skin feeling stripped.
We also sincerely appreciate you mentioning the slight stinging around the eye area. That kind of feedback is genuinely helpful for both us and other customers. The eye area can be especially delicate, so we completely understand your caution there.
And, we love hearing that it has become part of both your morning and evening routine alongside another 😊GoW cleanser.
Thank you again for your support, trust, and kindness toward our small company.
It means a great deal to us.
Markey
This clay is a wonderful ingredient I add to my tallow soaps I make
This clay is a wonderful ingredient I add to my tallow soaps I make. Extra creamy lather, plus all the benefits from Rhassoul clay.
Hi Helen :-D
This is wonderful to hear. Rhassoul Clay has some pretty spectacular properties and to know how it helped enhance
your soap sounds lovely.
Tallow soaps must be very conditioning and gentle to the skin. ;-)
Markey and the GoW Family 😊